SUNDRIES. 
167 
♦ 
but develop substances which have injurious effects upon 
animal cells. 
Such a mixture when freshly made has no healing proper¬ 
ties similar to glycozone. On the contrary glycozone is 
stable, harmless and always effective. 
Sanitary News. —From the Public Health of Minnesota, 
Dr. C. N. Hewitt the editor gives the following statistics for 
glanders in the State during the months of November and 
December, 1892. 
November, 1892.—Remaining on hand Nov. 1st, 38, 
killed during the month 3 ; reported during the month 7 ; re_ 
leased during the month o; remaining isolated Dec. 1st, 42. 
December, 1892.—Remaining on hand Dec. 1st, 42 ; 
killed during the month 3 ; reported during the month 4 ; re¬ 
leased during the month o; remaining isolated Jan. 1. 1893, 
11. 
Most of them “ suspects ” under observation. 
Comparative Action of Antipyrine, Phenacetine and 
Phenocoll. —From a series of experiments on dogs, Drs. 
Herna and Carter have reached the following conclusions: 
1. Antipyrine, phenacetine and phenocoll, all fail to produce 
any effect on the heat functions of the normal animal. 2. An¬ 
tipyrine produces a decided fall of temperature in the first 
hour after its administration in the fevered animal. This re¬ 
duction is due to a great decrease in heat production. 3. 
Phenacetine, both in septic and albumose fevers, produces a 
very slight fall of temperature during the first and second 
hours after its ingestion by the stomach, but the greatest re¬ 
duction occurs the third hour after its ingestion. The fall of 
temperature results chiefly from the heat dissipation. The 
increase in dissipation is not as great as with antipyrine. 
Probably the delayed action of the drug depends on its in¬ 
solubility. 4. Phenocoll causes in fever a very decided fall 
in temperature, which occurs the first hour after the admin¬ 
istration of the drug by the stomach. This reduction is the 
result of an enormous diminution of heat production, with¬ 
out any alteration of heat dissipation. Their experiments 
