168 
SUNDRIES. 
with antipyrine are in accord with the results obtained by 
Martin. Wood, Reichert and Hare, together with Destree, 
have reached the conclusion that antipyrine reduces the tem¬ 
perature by a decrease in heat production, and that heat dis¬ 
sipation also falls with the production. In their experiments 
with antipyrine the composite curve shows the rise of heat 
dissipation. The authors believe, therefore, that this phe¬ 
nomenon is effected through a thermotaxic rather than through 
a thermogenic mechanism. They further believe that phe- 
nacetine and phenocoll reduce the temperature by a decrease 
in the heat production through their action on a thermogenic 
nervous center. The fact that all drugs here studied fail to 
produce any effect on the normal heat function, proves that 
they affect these functions through the nervous system. Prob¬ 
ably the fact pointed out by Hare, that many investigators 
do not take into account other circumstances, such as tying 
animals down, and confinement in a box, may explain many 
of the results obtained by some observers in the normal ani¬ 
mal .—Medical Record . 
GOOD BUSINESS OPPORTUNITY. 
Qualified Veterinary Surgeon, obliged to leave a good established practice 
in best location in Pennsylvania, will give same to Veterinarian buying his 
office, infirmary and residence. 
For full particulars address, 
j j a A. B. C., care of American Veterinary Review. 
FOR SALE. 
Veterinary practice (established four years) in city of forty-five thousand 
•(45,000) in farming country. Only one other graduate within one hundred and 
ten miles. Cool summers. Good climate. Good schools. Price ($500) five 
hundred dollars cash. For particulars etc., apply, 
Dr. Poe, V. S., 
t f 0 Knoxville, Tennessee. 
