REVIEW OF BIOLOGY. 
201 
ACTION OF THE EXTRACT OF BOVINE BLOOD UPON ANIMALS 
% SUFFERING WITH GLANDERS. 
By A. Babes. 
The following- is the mode of extracting the active sub¬ 
stance from the blood of bovines: 
The blood obtained by bleeding is received into a steril¬ 
ized balloon, and left alone for several hours at a low temper¬ 
ature. A certain quantity of water is added to it, and then, 
little by little, zinc powder, the balloon being well shaken. 
The mixture is then filtered. 
The filtered liquid, which is clear and slightly colored, of 
a greenish brown, is treated with sulphuret of potash, to elim¬ 
inate the zinc; then undergoes a second filtration and concen¬ 
tration in a vacuum at a temperature of 35° C. 
The residue is then dissolved in a mixture of equal parts 
of sterilized water and glycerine, and the solution is ready 
for use. 
The cutaneous injection of this liquid in doses of occ.25 
extract of blood, is followed several hours after by a thermic 
reaction, very marked in the glanderous guinea-pig, but pro¬ 
ducing no change in the healthy animals. 
Experiments"’ made upon thirteen horses, both healthy and 
glanderous, have given the same results. Upon the healthy 
animals, no elevation of temperature; among those which 
had proved to be glanderous at the post-mortem, a well- 
marked elevation of temperature, continuing for from six to 
ten hours following the injection. The author is led by these 
results to the conclusion that the serum of the blood of 
bovines, besides the property of revealing the presence of 
glanders, possesses also a specific therapeutical and inocula¬ 
tive or developing action in that disease.— Ibid. 
UPON THE TRADMISSIBILITY OF THE MANGE OF THE CAT 
AND RABBIT DUE TO THE SARCOPTES MINOR FURST. 
By M. A. Railliet. 
But little was known of the transmissibility^ of this disease 
from one species to the other when the author had occasion 
to study the mange of the rabbit, and to make experiments as 
