202 
EXPERIMENTAL PATHOLOGY. 
to its ease of transmission. He has done the same thing 
with the mange of the cat, and has made the following Qon- 
clusions : 
1. It has been impossible to transmit the sarcoptic mange 
(due to sarcoptes minor) from the rabbit to the rabbit, to the 
cat, to the rat or to the dog. 
2. This affection was easily transmitted from cat to cat. 
3. It was transmitted only with great difficulty from the 
cat to the rabbit, and only after an extremely long period of 
inoculation. (Five months after cohabitation and three 
months after the death of the cat). 
Rabbits which contracted the disease from cats have given 
it to rabbits. 
For rabbits the degree of contagiosity must then necessarily 
be very weak.— Ibid. 
EXPERIMENTAL PATHOLOGY, 
THYROIDECTOMY—EFFECTS UPON THE NERVOUS CENTERS. 
By T. Capobianco. 
Entire thyroidectomy is always followed by death in man 
and also in dogs, in which when operated on, the temperature 
diminishes gradually from the moment of the operation until 
death, though rising somewhat during the convulsive attacks. 
The histological examination of the central and peripherical 
nervous system reveals circulatory troubles and peculiar 
modifications of the nervous element, such as atrophy, gran¬ 
ular and vacuolar degeneration with a predominance of one 
or other of these lesions according to the cases and the parts 
examined. These alterations are specially precocious in the 
brain (cerebrum) where the)^ principally assume the atrophic 
form. Cerebral lesions occupy principally the cells of Puck- 
inje, but are also found in the cortical layer and the dentated 
body. Among the bulbous nuclei, that of the hypoglossus is 
most commonly affected, then those of the facial, of the pneu- 
mogastric and the others. In the marrow, the lesions are in 
the gray and white substances, with predominance upon the 
