228 
E. LECLAINCHE AND L. MONTANE. 
on the periphery of the center, the inflamed alveolar cavit es 
unite to form the fibrous envelope of the tubercle. Rabe, 
again, insists upon the diversity of the pulmonary accidents 
observed in chronic glanders, and especially upon the altera¬ 
tions in the lymphatic vessels, the obstacles interposed to 
the circulation giving rise to a stasis of the lymph and to the 
oedema and gelatinous infiltration of the tissues, and later to 
their induration. This is the explanation of the lesions of 
the interlobular tissue and those of the lymphatic sheaths 
which surround the vessels and the bronchia. 
*Czokor studies only the glanderous tubercle, and dis¬ 
tinguishes it histologically from the lesions which are proper 
to true tuberculosis. When these are constituted bv an ir- 
«/ 
regular agglomeration of very small centers, the neoforma¬ 
tion of glanders always assumes a well-marked, rounded form, 
and is constituted at once by a single center of inflammation. 
The histological examination shows that the nodule of gland¬ 
ers begins with the cloudy tumefaction and dropping of the 
alveolar epithelium, and soon after, upon a section of the 
part, a central detritus appears composed of an accumulation 
of round, granular cells and dissociated vesicular walls. The 
degeneration becomes less marked as the examination re¬ 
cedes from the center, while at the periphery the round cells 
have kept their form and their characters. The central four 
are circumscribed by a compact zone, of variable thickness, 
formed by an infiltration of leuocytes in the alveoli, and lastly, 
a third external layer is composed of a dense, indurated cel¬ 
lular tissue, which constitutes an isolating envelop for the in¬ 
flammatory center: 
fLaulanie gives a very exact description of the old gland¬ 
erous tubercle. In the center is a caseo-purulent mass, very 
brittle, which can be squeezed out at the post mortem, and 
which very frequently drops off while specimens are being 
mounted ; around this central zone is another of proliferation, 
*Czokor, Vergleichende Patholog-anatom. Studien ueber den Rotz und die 
Tuberculose des Pferdes. Revue fur Thierheilkunde, 1885, 1886. 
fLaulanie, Etude critique and experiment ale sur les cellules geantes nor- 
males and pathologiques, Paris, 1888. 
