AN OUTBREAK OF SCARLET FEVER IN COLORADO. 
249 
membrane of the nasal passages, with the commencement of 
scarlet and purple spots, and great difficulty in swallowing. 
These symptoms were common to all the previous cases in 
the early stages. As a rule the symptoms gradually advanced 
to increased discharge from the nostrils—sometimes with 
blood—more or less ulceration of the nasal membranes, swell 
ing of one or both hind legs or between the fore legs, with 
multiple pustules on various parts of the, body, which on 
breaking off left sluggish ulcers. In cases where the swell¬ 
ing was very extensive the animal died in from ten days to 
three months. 
Of the sixteen animals examined thirteen had more or less 
discharge of a thick, glutinous charac er from one or both 
nostrils. All had either completely healed scars on the nasal 
membranes, showing a previously ulcerated condition, or had 
ulcers in now a healing condition ; one had perforation of the 
septum, four had no signs of ulceration either past or present; 
and ten had more or less enlargement of the glands of the jaw. 
A mule, which had also been turned out with the horses, and 
which had the disease in its most acute form together with 
extreme emaciation, was found to be perfectly healthy and 
the symptoms had entirely disappeared. Upon a general re¬ 
view of these symptoms, with a history of the disease, it is not 
to be wondered at that, considering its persistent character on 
this ranch, it should have been considered glanders. 
The main reasons determining a doubt, which afterwards 
culminated into a certainty, of its non-glanderous character, 
were that undoubtedly several horses had recovered absolutely, 
several more were in a fair way to recover and during the 
whole five years not a single case of direct infection to man 
or other animals at a distance could be proved; and, finally, 
the appearance of abscesses which frequently broke at m itur- 
ity, in several of the cases, which is the rarest circumstance 
in glanders. Having determined that the disease was not 
glanders, and not wishing any doubt to exist in the minds of 
the public, I represented to Mr. Johnson that the only way 
to settle the question absolutely, was to destroy the worst 
chronic case for post mortem examination. To this Mr. 
