STUDY OF PULMONARY GLANDERS. 
305 
sembling lymphodenoma. With a low power they appear 
under the pleura as a round mass, formed of ten or fifteen 
rounded or ovoid follicles, granular in appearance, situated 
in a stroma of similar aspect, but clearer and more condensed 
at the periphery in a surrounding envelope. The aspect is 
that of a lymphatic gland. The lesion is developed on the 
course of an interlobular band, a short distance from its union 
with the pleura. The band may be clearly seen divided into 
two fasciculi, which separates in order to surround the neo¬ 
formation. One pushed toward the pleura is confounded with 
it, while the other separates the diseased focus from the sur¬ 
rounding pulmonary structure, which has remained healthy. 
The nearest alveoli, compressed and flattened, present them¬ 
selves under the form of narrow and irregular fissures. With 
a stronger power the follicles/ were seen to be gorged with 
leucocytes well colored, and provided with a large nucleoli. 
Here there is an appearance of larger elements, with yellow¬ 
ish protoplasm, finely granular, forming grayish spots on the 
dark, rosy bottom of the section. Running through the fol¬ 
licles there is a delicate network of lymphatic capillaries, and 
between the elements a fine, connective reticulum is observed. 
The spots occupying the center of the lesion contain elements 
orange red in color, and having a brilliant homogeneous ap¬ 
pearance, which have undergone a certain degree of vitreous 
or waxy degeneration. 
In the interfollicular septa, short glanders bacilli are seen, 
small in numbers, but perfect in form. Their presence is 
made more difficult to determine in the follicles by the strong 
coloration of the round cells ; they are detected, however, in 
the wide spaces situated around the walls. 
These pseudo-tubercles are in the perilobular connective 
tissue, or in the interalveolar partitions, while the inflamed 
connective tissue of the surrounding regions reminds one of 
the normal reticulated tissue, so these neoformations are 
strongly suggestive of the lymphodenoma, the resemblance 
becoming still closer if it be admitted that the reticulum of 
the lymphoid tissues is a cellular network, as Laguesse* has 
Laguesse —(Development of the spleen in fishes). 
