374 
E. LECLAINOHE AND L. MONTANE. 
Like the tubercle, the pneumonia takes place near the 
pleura, or the interlobular travea, or at time • in the sub- 
pleural portions joining two lobules. The pleura, the septa 
and the alveolar walls are thickened, oedematous and infiltrated 
with leucocytes. The alveoli are entirely filled with a fibrin¬ 
ous exudate, and a large accumulation of round cells in pro¬ 
cess of degeneration. A few of the elements have preserved 
their normal aspect and the smoothness of their outlines ; 
others are indicated only by irregular granulation, represent¬ 
ing nuclei destroyed during their segmentation. The alveolar 
epithelium has entirely disappeared. Over the whole extent 
of the diseased center, large numbers of small bacilli may be 
found elongated, more or less separated ; very abundant in 
the alveolar contents, they are disseminated in the walls among 
the degenerated cellular elements. 
This portion of the affected lobule represents a rounded 
grape, surrounded by a narrow zone of catarrhal pneumonia. 
In the remaining portion of the lobule and especially in the 
neighborhood of the diseased center, the vessels are gorged 
with blood, and disseminated hemorrhages are found in the 
alveola. Bacilli are again detected here, but in much smaller 
numbers. 
These lesions exactly reproduce what is observed in acute 
glanders, differing from those by their limited localization. 
D.— Vascular and Bronchiau Alterations. 
The initial lesions of the lymphatic tracts extend rapidly to 
the sheaths which surround the vessels and the bronchia. 
During the first periods of the disease, large accumulations 
of leucocytes appear in the spots affected, around the large 
vessels, distending the adventitious tunic and transforming it 
into a large annular lymphatic sheath. A little later, the walls 
of the vessel undergo marked alterations : round cells pene¬ 
trate into the middle tunic, while the endothelium swells, 
proliferates and becomes loose. The leucocytes infiltrate all 
the walls, and break into the vessels, and with them enter 
numerous bacilli; some free, others enclosed in the cells. The 
imported leucocytes have, most of them, undergone a be- 
