' 378 
E. LECLAINCHE AND L. MONTANE. 
animal may be found free from the lesions of pulmonary 
glanders after a minute autopsy, when in reality numerous 
bacilli may exist in some parts of the lung in the bronchia of 
infected regions, and consequently in the discharge. Al¬ 
though the absence of pulmonary tubercles may appear to 
be established, even after a post-mortem examination, it does 
not necessarily imply the non-existence of glanders, and that 
is a fact not at present without interest. 
Conclusions. 
i 
To resume: First. In chronic glanders in the horse, the 
infection of the lung takes place through the lymphatic tracts, 
and is manifested by tuberculous neoformations as well as by 
alterations of the blood vessels and of the bronchii. 
Second. The glanders tubercle starts by a peri-lobular 
lymphangitis ; the lobule is attacked secondarily from the 
periphery to the center; the first anatomical indication of the 
tubercle being a nucleus of fibrinous pneumonia. The mid¬ 
dle of the diseased focus becomes afterward the seat of a leu¬ 
cocytal apoplexy, followed by the caseous degeneration of 
the elements, with a peripherical reaction, which attains to 
the development of an epitheloid belt lined with a connective 
envelope. 
Third. A peculiar anatomical form is due to the develop¬ 
ment of agminated lymphoid centers in the interlobular sep¬ 
ta, in which form the pseudo-tubercle much resembles, his¬ 
tologically, the lymp hade noma. 
Fourth. An exceptional alteration is constituted by the 
development of a center of alveolar pneumonia, surrounded 
by a hemorrhagic zone. This form constitutes a very limited 
focus of acute glanders. 
Fifth. The blood vessels and the bronchii from the first 
stages of their development undergo important alterations. 
Their inflamed walls are penetrated by leucocytes and bacilli, 
which have been introduced through the medium of the lym¬ 
phatic sheaths. Even when the lesions are very small, and 
in appearance localized, bacilli appear in the blood ; and again, 
they are found in abundance in the bronchia, and consequently 
in the discharge. 
