SILVER SALTS OF CREDE AND THEIR APPLICATIONS. 21 
and especially as to their application in surgery, are very favor¬ 
able. The advantages-are that by their use the wound secretion 
is diminished to the minimum, and thereby healing of the 
wound by first intention is facilitated ; unhealthy wounds, with 
no tendency to heal, abrased surfaces, fistulae, punctured 
wounds, etc., treated with mild solutions of these salts, terminate 
in most instances very favorably in a very short time. 
I observed in cases of plantar neurectomy healing by pri¬ 
mary intention, treating the wound with a 1:2000 solution of 
argentum colloidale. I also obtained very good results from 
the application of the powder of citrate of silver in punctured 
wounds of the foot, and, following the advice of Prof. Fan- 
zillotti, to disinfect the foot with a 1 per cent, solution of the 
citrate of silver, then to cut down on the wound and dress with 
the powder of citrate of silver. There is no need to renew the 
dressing for three or four or even five days, after which we will 
find a dry healthy wound with a broad rim of new formed horn. 
Dieckerhoff, Baldoni, and others, experimented with the 
argentum colloidale as a diagnostic agent for glanders, the re¬ 
sults of which are not very satisfactory. It was proven that 
an injection of argentum colloidale intravenously will cause a 
more marked temperature reaction in glandered horses than 
malleine, but, on the other hand, it was observed that a re¬ 
action took place in other diseased conditions than glanders, 
but this condition we are apt to get with the use of malleine 
also. I tested a horse with collargol, which manifested all 
the characteristic symptoms of glanders. The result of this 
test was a reaction of 5 0 F., while the same horse in a test with 
malleine showed only a reaction of 3J- 0 F. But as I did not 
employ the drug for the test sufficiently to pass an opinion on 
it, I will conclude from the experience of others, which, when 
taken into consideration, does not seem to be reliable enough 
to condemn an animal, just on the reaction of this test. Fur¬ 
ther experiments will teach us more about it, as the drug has 
not been tried enough to form a definite opinion as to its diag¬ 
nostic value. 
