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at one time the fifth, then the eighth, or another sound ceased ; 
sometimes the systolic, other times the diastolic sound was ab¬ 
sent. Eleven minutes after splitting of the sounds as before 
was audible. The weak, small, empty and irregular pulse was 
30 per minute, and on the following day 28. From now on on 
the consecutive days the number of pulse beats were diminished 
to 24, r6, 14, etc., to observe on the 22d day a diminishing to 
8 beats, which was never seen yet. To strengthen the dimin¬ 
ished action of the heart, the patient received 500.0 gm. alcohol 
in two doses, and three times 10.0 gm. doses of the tinct. of 
strophanthus daily ; also Carlsbad salts and winesups, but all 
failed to prove successful. The horse died with the appearance 
of great dyspnoea and attacks of convulsive spasms. Autopsy : 
Gastritis composa, enteritis haemorrhagica, haemorrhagica sub- 
epicarditis, degeneratio parenchymatosa myocardii. The author 
considers the pronounced bradycardia as reflectoric produced 
by the diseased condition of the stomach and intestines, in 
which the irritation of the nerve fibres in the walls of the 
stomach, was forwarded in a centripetal direction to the vagus 
centre, where it was transmitted to the inhibitory fibres of the 
same nerve, causing the bradycardia. The parenchymatous 
degeneration of the heart muscle, which often would accelerate 
the heart’s action, is to be considered as a result of the existing 
condition. Further to be seen m this case, that the bradycardia 
was symptomatic, which in favorable termination of the diseased 
condition of the stomach and intestines, presumptively would 
have caused only a transitory diminution in the number of 
pulse beats.—(. Koch's Monatschrijt .) 
To the Differential Diagnosis of Tristeza* and 
Anthrax \^Ligniere \.—Tristeza can be very readily mistaken for 
anthrax, but regarding the symptoms and the course of the two 
diseases, a distinct differentiation is possible. In most cases of 
anthrax the disease runs a rapid course, so that we hardly ever 
see the animal sick ; recovery is an exception. The mucous 
membranes are of a violet color. In tristeza we also may observe 
cases running a rapid course, but as a general rule the disease 
lasts from four to eight days. Recovery is more frequent, the 
mucous membranes are very pale. In tristeza there is always 
haemoglobinuria; in anthrax in cattle haeinaturia might be 
present in exceptional cases. The faeces in anthrax are very 
loose, and mostly of a bloody color, while in tristeza they are 
* Tristeza, as proved by Ligniere’s investigations in Argentina, is the same 
disease as Texas fever in this country. See January (1901) Review, page 754. 
