BOVINE TUBERCULOSIS. 
323 
reactions on the 9th as follows : 3.30 A. m. 39.5, 6.30 A. m. 40, 
9.30 A. M. 39.7, 12.30 P. m. 39.6. 
The continued use of tuberculin did not prevent a reaction. 
Close observation of this animal from the first reaction 
showed short breathing, a certain cough, short, irregular at 
rather long intervals. Good appetite and airiness lasted until 
her departure on the 9th of June. 
As regards Cow No. 5, the infection did not manifest itself 
until after the tuberculin test of June 8th, when the following 
temperatures were noted : 3.30 A. m. 40, 6.30 a. m. 39.5, 9.30 A. 
m. 38.6, 12.30, 39.8. This high temperature remained the whole 
of next day, 39.5. 
June 14th she was again injected with tuberculin and the 
following temperatures were noted : 6 a. m. 41, 9 a. m. 40, noon 
40.3, 3 P. M. 40-6, 6 P. M. 40.4 ; the hypothermic state lasted for 
forty-eight hours. 
On the 21st of June the resistance to the action of tuberculin 
began to manifest itself, but it ended on the 28th of same 
month. Both animals were really infected ; No. 5 on the 32d 
day ; No. 6 on the 19th day. With both immunity was very 
slight and slow to come. 
A utopsies. 
Cow No. 5 (killed July 2d).—The mouth, the pharynx, the 
larynx and the trachea, the glands of the throat region and of 
the pharynx appear to be free from all lesions. Both lungs are 
filled with a considerable number of miliary tubercles, the sizes 
of which vary from those of a cabbage seed to those of a small 
pea ; many are still translucent ; many also show in the centre 
an opaque, whitish or yellowish spot ; a few, the larger, are 
hard, dense and yellow. A cut shows them to be formed of a 
fibrous shell containing caseic substance, not yet softened or 
calcarious. Nowhere does the pulmonary tissue appear to 
be congested or inflamed, not even in their immediate vi¬ 
cinity. All the bronchial and mediastinal glands are hy¬ 
pertrophied, hard, knotty, overfilled with a milky sejosity; 
they show’ in their cortical layer a great number of miliary 
