420 
NOCARD AND ROSSIGNOL. 
abdomen is tucked up; respirations 70 and pulsation 100 per 
minute, trembling of muscles of the thighs and shoulders, the 
respirations now are plaintive and interrupted. 
She has not eaten since June 3, and June 6 during the 
night she died. 
Autopsy . 
All the viscera, lung, liver, spleen, kidney, udder, lymphat¬ 
ics, bony marrow, are infiltrated with an incredible quantity of 
extremely fine nodules,which when cut through give to the finger 
a gritty sensation. It is a typical case of acute miliary tubercu¬ 
losis. The histological examination of the pulmonary tissue 
shows it to be formed almost exclusively of embryonic nodules, be¬ 
ing hardly one half millimeter in diameter ; so numerous are they 
and so close together that the permeable tissue between them is 
hardly equal to the space which they themselves occupy. The 
central cells of the nodules are in process of caseification. They 
are infiltrated with Koch’s bacilli, less numerous than one would 
expect. 
FIFTH LOT, COWS IO AND II — INTRA-MAMMARY INJECTION 
OF TUBERCULAR EMULSION. 
The 10th of May, the second day after the injection, the 
teats of cow No. 10 are tumefied, hot, sensitive to touch, the 
milking becomes difficult and painful and gives a clotty curdled 
milk, and in the evening a slight hyperthermy, 39°.i ; the other 
teats are normal. 
May 11, 12, 13, and 14 the mammae increase in volume and 
sensitiveness ; the corresponding teats are hard and turgescent. 
It is with difficulty that a few drops of curdled milk are drawn 
from the diseased teats. The temperature remains between 40° 
and 40°.5 until the 14th, when the animals were subjected to 
the first tuberculin test, but it was without effect, the tempera¬ 
ture not increasing during the 15th of May. On that day, how¬ 
ever, this cow is dejected, has an arched back, and is at the end 
of her chain when standing ; but she prefers to lie down, eats 
but very little, and her teats have increased in volume. 
Until May 20 her condition isstationary, her appetite always 
