422 
NOCARD AND ROSSIGNOL. 
0.770 kilo. Considerable oedema extends around the diseased 
mammae and spreads under the abdomen beyond the umbilicus. 
The two inoculated glands are invaded throughout by the 
tubercular infiltration. When cut they present a rosy color 
somewhat yellowish ; their lobes are coarser, due to the increase 
of connective tissues, giving to the touch the sensation of a 
rasp. The galactophorous sinuses are distended by a yellow 
serosity containing fibrino-purulent clots. The mucous mem¬ 
brane is thickened, infiltrated, hyperaemic, pimply and ulcerated 
in places. Here and there on the red substratum of mucous 
membrane are seen yellowish points due to the presence of 
specific miliary nodules. 
The mammary lymphatics are five times their normal size, 
being distended with serosity ; their cortical layer is filled with 
tuberculous granulations already casefied. The precrural lym¬ 
phatics present the same lesions though less pronounced. The 
sub-lumbar ganglions are also affected, but the changes diminish 
in intensity from the rear to the front. The most posterior are 
almost the size of a kidney, while near the mesenteric artery 
they have hardly increased in volume, beyond that they are 
normal. 
It is plainly seen that, from the mamma the infection has 
spread slowly toward the centre through the lymphatics. Death 
was caused by tubercular intoxication, before the infection had 
reached the viscera. In fact, the viscerse of the thorax and ab¬ 
domen are absolutely free from all tubercular lesions. 
The bacteriological examination of the mammary tissue 
shows an enormous numher of Koch’s bacilli, mostly free. 
Until May 21, that is thirteen days after the virulent inocu¬ 
lation, Cow No. 11 has maintained a normal temperature. It 
went to 39.5 and 39.8 as a result of an injection of tuberculin 
May 20. The first symptoms of mammitis is shown around the 
left anterior and right posterior teats; the quarters became hy¬ 
pertrophied, hot, sensitive, and the milk is clotted and curdled. 
There is hyperthermy and- hypothermy until May 25. On 
the 26th, the day of testing, the temperature is 40°. The next 
