I 
712 JOHN J. REPP. 
Ravenel 6 8 also reports the following two cases : 
“ On January i, 1900, my assistant, Mr. G., while perform¬ 
ing a post-mortem on a goat which had succumbed to experi¬ 
mental inoculation with a culture of bovine tubercle bacillus, 
scratched his knuckle on the broken ends of the ribs. Within 
a half hour the wound was washed out with a 1:1000 solution of 
mercuric chlorid, and sealed. It healed promptly, but about 
three weeks after became reddened, swollen, and sensitive, es¬ 
pecially on motion. It was protected, but grew worse, and on 
February 27 Dr. C. H, Frazier excised the nodule, with a mar¬ 
gin of healthy skin. With one half of the nodule we inoculated 
2 guinea-pigs subcutaneously, and the other part was prepared 
for sections. These sections show an infiltration process which 
encroaches on the papillary layer of the skin, some of the papil¬ 
lae being destroyed. No typical giant-cells can be made out. 
None of the sections were stained for tubercle bacilli. On May 
5, one of the inoculated pigs died and the other was killed. 
Both of them showed a generalized tuberculosis involving the 
chest cavity as well as the abdomen. There has been no return 
of the lesion so far. 
“ The other case is that of a well known veterinarian of 
Philadelphia, who, in making an autopsy on a tuberculous cow, 
wounded the knuckle of his forefinger. Between 3 and 4 weeks 
after, the scar was noticed to be enlarged, reddened, and some¬ 
what sensitive. As it showed no tendency to improve, but 
rather grew worse, some 6 weeks after it was first noticed it was 
excised by Dr. H. W. Cattell, and the wound cauterized with 
bromin, since which there has been no return. The nodule 
was examined by Dr. John Guiteras, who demonstrated its 
tuberculous nature by finding tubercle bacilli in sections.” 
Further evidence than this is not on record so far as I have 
been able to ascertain. Whatever our conclusions may be they 
must be drawn from this evidence together with some corrobo¬ 
rative evidence of another character, which will be referred to 
later on. Those who are in search of more convincing evidence 
of the pathogenicity of the bacillus of animal tuberculosis for 
1 
