734 
M. H. J. P. THOMASSEN. 
lesions of tuberculosis of the ox the same characteristics as in 
those of man. 
The anatomo-pathologists, with Virchow at their head, de¬ 
fended, during a number of years, the opinion that pearl-disease 
of cattle is a disease entirely distinct from human tuberculosis. 
It was not until 1882 that the discovery of the bacillus of Koch 
and its constant presence in' the specific lesions of all the spe¬ 
cies triumphed over the last resistance on their part. In the 
meanwhile, during the period between 1865 and 1882, a num¬ 
ber of learned men have busied themselves to prove the identity 
of the two tuberculoses, and have done so with success. 
As proof, it was necessary to take the virus from one species 
and cause it to develop in the other. Of course, there could 
only be question of an infection from man to animal. In case 
one succeeded in one sense, the opposite should be regarded as 
very probable. It is Chauveau who, at the veterinary school of 
Lyons, made the first attempts in 1868. The infection of the 
bovine species by human tuberculous virus was brought about 
in three manners: by the introduction of tuberculous matter 
into the digestive organs, by intravenous injection, and by the 
injection into the subcutaneous connective tissue. Three sub¬ 
jects who swallowed infectious material derived from human 
lesions became all tuberculous. The lesions had the same 
character as those of animals which had ingested material ob¬ 
tained from bovine lesions. 
In one single case the human virus was introduced intrave- 
nously ; after 29 days the injection had already caused the for¬ 
mation of interesting lesions, all localized in the chest. The 
hypodermic injection of a tuberculous emulsion, derived from 
the human species, gave rise to a local tuberculosis, with at the 
most, lesions in the nearest lymph node, without the least mani¬ 
festation of a generalization of the infection. 
The author conies to the conclusion, that human tuberculous 
virus behaves itself toward the bovine species as tuberculous 
virus derived from the same species. Klebs inoculated a calf 
of four weeks into the peritoneum with tuberculous material 
