272 
Journal of Agricultural Research 
Vol. V, No. 7 
A week after recovery it was started on feed 319 (precipitated gossypol 
on com meal). We planned to have it eat 0.3 gm. of gossypol daily. The 
first week 0.38 gm. of precipitated gossypol was eaten, the second week 
0.67 gm., and only 0.60 gm. thereafter, a total of 1.65 gm. Death ensued 
after 19 days. The animal ate feed 319 sparingly and very irregularly. 
A young rabbit (962) was fed similarly at the rate of 0.14 gm. a day. 
By weeks it ate, respectively, 0.97, 0.15,0.15, and 0.34 gm. of precipitated 
gossypol. It was normal after the first week and died on the twenty- 
ninth day. 
A guinea pig refused to do anything more than nibble feed 318 (gossy¬ 
pol extract), eating in 29 days only 34 gm. of the feed. It could not 
be induced to eat feed 319 (precipitated gossypol) any better, consuming 
only 1.13 gm. in 27 days. The autopsy showed that a mesenteric twist 
had cut off the blood supply of the last half or third of the intestines, 
so that death was not directly traceable to the feed. 
Rabbit 949 was fed a large dose (1.44 gm.) of the precipitated gossypol 
mixed with com meal and molasses. The next two days it suffered 
from diarrhea and refused to eat this feed, but it ate green feed. There¬ 
after it was given precipitated gossypol in small doses, but it usually 
refused all or part of this. Steadily losing weight, the animal died after 
35 days, having eaten a total of 4.47 gm. of gossypol, inclusive of the 
large dose. The amounts eaten each week were, respectively, 2.08, 
0.58, 0.50, and 0.68 gm. 
Rabbit 937 had previously eaten the ether-extracted residue (feed 
316) for 61 days and had increased in weight. Then, after several days 
on corn meal and molasses the rabbit was fed precipitated gossypol. 
We planned to feed 0.3 gm. a day, but only on three days did it eat this 
amount, usually refusing it entirely or in part. After 21 days a crys¬ 
talline product was substituted for precipitated gossypol. The animal 
steaffily decreased in weight and died after 33 days. The total amount 
of gossypol consumed was 2.52 gm. By weeks, 1.19, 0.27, 0.5, 0.57, 
and o gm. of gossypol were consumed. It ate practically nothing 
during the last 8 days. See Table V. 
Table V .—Results of feeding precipitated gossypol with com meal and molasses (feed 31Q) 
to rabbits and guinea pigs 
Animal No. 
Weight of animal. 
Weight of 
precipi¬ 
tated 
gossypol 
eaten. 
Number 
of days 
fed. 
Result. 
Initial. 
Final. 
Loss. 
Rabbit 954. 
Rabbit 961. 
Gm. 
1,740 
1,830 
Gm . 
*>275 
i >435 
465 
Gm . 
465 
395 
1. 02 
1. 22 
13 
19 
Died. 
Do. 
Rabbit 962. 
630 
165 
1. 62 
29 
Do. 
Guinea pig A. 
660 
565 
95 
*3 
27 
Do. 
Rabbit 949. 
2,375 
2,890 
1, 702 
673 
a 4 • 47 
35 
Do. 
Rabbit 937. 
*> 9 2 5 
965 
2. 50 
33 
Do. 
®This quantity (4.47 gm.) includes a large dose of 1.44 gm. which evidently passed the bowel quickly. 
