Dec. 27, 1915 
Diuresis and Milk Flow 
565 
possible that the previous severe regime of sodium acetate and purin 
feeding may have injured the kidneys sufficiently to account for the 
results obtained. 
In other trials it was repeatedly demonstrated that the administration 
of urea upon consecutive days would not continue to influence milk secre¬ 
tion even though diuresis obtained. This is brought out in Table IV. 
Table IV .—Effect of repeated urea administration on the milk flow of goat I 
Date, 
Water. 
Urine. 
Milk. 
Solids. 
Fat. 
Nitro¬ 
gen 
in s c. c. 
Remarks. 
Jan. 15... 
C.c. 
1,850 
C. c. 
h 135 
C. c. 
880 
Per cl. 
15. OO 
Per ct. 
5 - 6 
Mgm. 
33-5 
No additions to ration. 
l6. . . 
2, 500 
2,850 
975 
840 
14.85 
5-0 
33 - 5 
Do. 
17 ... 
1,125 
1,685 
840 
14. 56 
5-4 
34-3 
Do. 
18... 
3,000 
710 
16. 55 
6.5 
35.1 
Collection from 30 gm. of 
19 ... 
3, 550 
2,100 
850 
15. 72 
6.4 
32.3 
urea. 
Do. 
20. . . 
4,000 
2,410 
1,625 
780 
16. 12 
6.8 
32.2 
Do. 
21. . . 
3,000 
845 
15.85 
6.15 
31.6 
Do. 
22. . . 
3, 000 
735 
965 
15 . IO 
5 - 7 
31- 7 
No additions to ration. 
23 ... 
4,100 
345 
850 
I 5 - °7 
5-4 
33 - 5 
Do. 
24... 
2,075 
S 2 5 
875 
15. OO 
5-25 
33*9 
Do. 
It is significant that the consumption of water upon repeated admin¬ 
istrations of urea increases with the diuresis. Whatever factors may be 
responsible for the symptoms of increased thirst when urea is given, 
they do not become operative until the water supply of the body is drawn 
upon so heavily that milk secretion is reduced. The stimulation of the 
mechanism for maintaining the concentration of the body fluids normal is 
then sufficient to cause the animal to imbibe enough water for all its 
excretory and secretory processes. 
In this connection it was of great interest to determine the effect of the 
administration of sodium chlorid upon milk secretion. Table V gives 
the data obtained with goat 2. 
Table V .—Effect of sodium chlorid on the milk flow of goat 2 
Date. 
Water. 
Urine, 
Milk. 
Solids. 
Fat. 
Nitro¬ 
gen 
in 5 c. c. 
Remarks. 
July 19... 
C. c. 
1,500 
C. c. 
190 
C. c. 
410 
Per ct. 
16. 13 
Per ct. 
6.8 
Mgm. 
3 °* 4 
No additions to ration. 
20. . . 
I, 050 
155 
39 ° 
16. 25 
6. 5 
3 °* 4 
Do. 
21. . . 
2,800 
355 
420 
15 . 58 
6. 2 
30.3 
Collection from 20 gm. of 
22. . . 
i,i 75 
355 
400 
i 5 * 9 i 
6. 6 
30*3 
sodium chlorid. 
No additions to ration. 
23... 
i ,475 
160 
375 
15*44 
6. 7 
29. 2 
Do. 
24. . . 
2,425 
580 
410 
14 . 59 
5.5 
28.8 
Collection from 20 gm. of 
25... 
1, 050 
330 
4 i 5 
14 * 45 
5*7 
27.9 
sodium chlorid. 
No additions to ration. 
26. . . 
800 
170 
395 
14.77 
5*7 
29. 0 
Do. 
