Sept. 2,1918 
Comparative Toxicity of Cottonseed Products 
429 
therefrom were also secured. The steam pressures in the jackets sur¬ 
rounding the various drums ranged from 20 to 40 pounds. 
Since this long cooking period represents the upper limit of time and 
thoroughness of cooking in the cottonseed industry, the results of our 
rabbit and swine experiments especially are highly significant, in view of 
the claims that cottonseed-meal injury is a matter of dietary deficiency, 
Fig. i. —Graphs showing the toxicity of cottonseed meal and kernels to rats. The upper curves represent 
the records of rats fed cottonseed kernels cooked various lengths of time in a commercial oil mill. A 
marked change in toxicity occurs between the 10- and 20-minute interval. The lower curves show the 
fff pr -t of the meal made from the kernels cooked for 28 minutes and also the beneficial effect of ether 
extraction. The record of the rats fed soybean meal shows what growth might be expected if the diets 
had been free from toxic substances. The composition of the diets is given on page 431. 
and with reference to the conclusion by Osborne and Mendel (8) from the 
results of their rat experiments that the— 
treatment of cottonseed so as at least to render it harmless now seems to lie within 
the range of ready possibilities. 
A sample of the long-cooked meal used in the pig diets, also in the rabbit, 
rat, and poultry diets, was sent to Dr. T. B. Osborne, at the Connecticut 
Agricultural Experiment Station, who wrote as follows: 
Our results with the cottonseed meal from the French cooker show that this treat¬ 
ment has apparently entirely destroyed the toxic properties of the seed. All of our 
rats on this product are growing finely. 
In these experiments Dr. Osborne supplemented the meal with protein- 
free milk and butter fat. It is evident that the results with rats do not 
indicate what effect meal has on rabbits and pigs. 
