412 
is convenient also for adults, for they can be given a hundred pills at 
a time, which last a month. I do not like to exceed o'l gm. thrice a 
day. Calomel I do not value for antisyphilitic treatment; but for 
general use in dispensary work the liq. hydrarg. perch, in a mixture is 
the most useful. I generally colour this lightly with methyl blue, 
which gives an impressive and distinctive value to the bottle. One 
should begin at the rate of 2 c.cm. of liq. hydrag. perch, per day— say, 
10 minims three times a day, and increase to 3 c.cm. It is hardly 
necessary to go higher than this. Children bear this and any 
mercury well in proportion to the adults. For an infant of three 
months with inherited disease I give O' 15 c.cm. three times a day, 
equal to about two and a half minims. 
Intramuscular injection of soluble salts is, however, far the best 
mode of administering mercury in my experience. I cannot speak of 
the insoluble preparations, for, being quite satisfied with the salalem- 
broth, I have not tried the emulsion of metallic mercury so highly 
spoken of by some. In spite of the pain, I have found that out¬ 
patients attend very well. Out of a number who were to take six 
injections each, the average attendance was five times. I have used 
this method on infants with hereditary syphilis also, and in yaws. 
My experience is not yet very large, but I have had abundant 
opportunity of proving that some negroes can carry up to i'5 c.cm. of a 
2 per cent, solution of mercury perchloride without any sign of spongy 
gums. This is equivalent tp nearly half a grain of the salt, or about 
half an ounce of liq. hydrag. perch. Usually, I begin with 07 c.cm. and 
work up to I'O, using a solution containing mercury perchloride 2 per 
cent., ammonium chloride 1 per cent, and giving one injection weekly. 
With care, washing the buttock with an antiseptic and then with 
ether, I have not yet seen an abscess result, and only rarely any 
induration. For hospital treatment, or for regular yaws dispensaries, 
the intramuscular method should be the most certain, the easiest and 
most effectual method of giving mercury. The treatment is shorter, 
and for that reason more useful in the case of natives. It should be 
possible to get most cases to attend for six or eight weeks for a course 
o injections, and repeat this twice more within the first year. After 
is, one attendance a month for another six months. The symptoms 
that may be expected should be explained to the patient, in order that 
0 ma ^ at ° nce re P ort himself on the occurrence of any of them; and 
