45 6 
rapidly disintegrates, the outline of the cell becomes lost, and 
flagellum together with the extra-nuclear ccntrosome i. i\ 
frequently seen detached, and lying loose among the cells : 
organs examined (see fig. 26). 
These phenomena, as we have said, are encountered in the lun. 
but they are also found in the bone marrow and the spleen. Asa: 
the above stage has been reached the nuclear bodies and the 
disintegrating remains of the parent cells disappear to a large extra: 
from the lungs, the nuclear bodies being subsequently found in v<-:. 
large numbers both in the spleen and the bone marrow. 
At first sight, the appearance we have ju>t described might o 
supposed to be simply a phase in the disintegration of the parasites, 
and this was, as a matter of fact, the view winch wc were at fiat 
inclined to adopt. I here are, however, reasons for thinking that 
although the greater part of the protoplasm forming the bodies ot ti.< 
parasites undoubtedly does disappear, the peculiar nuclear structures 
we have just been considering do not follow the same course. Aft 
their detachment from the rest of the disintegrating cell body, the 
nuclear corpuscles become impacted in great numbers in the spier: 
and bone marrow. Here, instead of disap, in the course of a 
few hours, they may remain intact for as | ten days 01 
m act, throughout the whole of the negative or latent period of the 
infection, when no parasites are present in the peripheral Uood 
toterT /1 *Ti° rmati0n ’ these pccui: - • Which we propose 
although they thus rema.n intact for a relatively Jong peri* it 
a f ex Pcriment., Vol. 18 No , T 1 hu »- Rode ‘ “ d V*IH 
inniar to the latent bodies of 4 * descr, be bodies mrh; 
Bradford^ (C) ' h ' ?*** ™ ■» . 
Bradford (Q ua r. Journ. Micro Sri v, 1 ' "'* te form * Phmioer 
m the spleen, &c., during Nap ana ini* - ****** also to have found tbu 
similar bnm plas ™ odial production LaJer tl ' Scr,be ,hem apparently tb 
s.nnlar bod.es as ‘‘formes dmvoluhon ” and ' -scribi^apjOfU 
»i£ P TnV°* have seen them in the blood 8 T Vet Sc. Vol j 
he?..?™ .-TtaSS irs 
Xo. 1 
indicium, and to reg^ them “ blood °f caiUe in 
d H etS e thF?o u r rna l of 
a^e^ I SSi 0 LH- PreCisel > r V : ' ' 
details of r® b ? d,es as true portion ; e -. •'» th.- : . - • - - -• < 
The latent bo f d,V latl0, V 0f the lat eEt bodies in th' 
correspond to m u We have dealt with n r * pU{ ’ - 
espond to the bodies figured by Soiazek Vn^c '^ P«Uly * 
