4 7 6 
PLATE XL 
Stages in the Metamorphosis of Trypanosoma gambiense in the Organ\ 
Figs. 22, 23, 24, 26, 27, 28, 29, 30, 31, 32, 34, 35, 36, stained with a 
modification of Heidenhain. 
Figs. 25 and 33 stained with Breinl. 
Fig. 22. — Trypanosome during the decrease of the parasites in the 
blood of a rat, showing alteration in the nucleus marked 
by the formation of a vacuole. 
Fig. 23.—The same. 
Fig. 24. — One of the common forms in the lung at this period. 
showing the same changes in the nucleus. 
Fig. 26. Low power view of trypanosome at this period, showing 
the detachment of the latent body from the parent cell 
big. 27. Latent bodies. The nucleus is attached to a vacuole and 
both are surrounded by a thin film of protoplasm. The 
nucleus contains a single intra nuclear centrosome. 
Fig. 28. Latent bodies. To the left the intra nuclear centrosome is 
shown divided. To the right stages in the division of this 
body and the extrusion of one daughter element from the 
nucleus. 
Fig. 29. Latent bodies showing origin of a new flagellum from th 
mtra-nuclear centrosome. 
Figs. 30, 31— Later stages in the formation of small trypanosome 
from the latent bodies. 
F.g- 32 —Latent body from the spleen of a rat infected wit 
trypanosoma brucci, showing nucleus, vacuole, and th 
gin o t e flagellum from the intra nuclear centrosomi 
(Compare fig. 29.) 
F ’g- 33 — Trypanosome showing Mr i„ ♦ . . 
nucleus ^ ear ly stages in division of thi 
34 - —Trypanosome drawn to show thn c 1 1 
of the protoplasm Schaumplasma struct™ 
F'gs. 34 to 36.—The 
same. 
