divided at 3 30. Another observation showed the area commenting 
to be visible at I *5 5 » very bright after two minutes with the little 
tongue plainly visible ; it was not so bright at 2, and had vanished 
at 2’03 ; at this time division of the cytoplasm was well advanced. 
Another tongue and area was very bright at 2'oj, and gone at 2*26. 
In one case just before its disappearance, the little halo divided, 
showing a delicate, thread-like connection between two dots (fig. 14). 
These separated completely into two (fig. 15), and then both 
disappeared. 
A dot was sometimes discernible at one end of the “tongue." 
Clear areas, smaller and quite distinct from those described above, 
occasionally appeared for a few seconds in the cytoplasm of the 
trypanosomes before the first division. One of the products of the 
first division not infrequently divides before the other. Often one 
or two of the products of the third, fourth or later divisions divides 
no further. Indeed, the development of the parasite may be arrested 
at any stage. Such individuals become rounded and very granular 
and probably usually disintegrate. Some of them may become 
encysted resistant forms. 6 
In dividing, the cells rotate one upon the other in opposite 
irections, so that the long axis of one comes to lie at right angles 
to that of the other (fig. 16). The nuclei were indistinct. The time 
taken to turn around in one case was about thirty minutes. 
In one instance the single rounded organism had divided, in fiv' e 
our 3 a " d forty-two minutes, into sixteen cells, which were all 
apparent y inside the outer covering of the original trypanosome 
^ S- 17;. In six hours and a half, many of the cells had divided 
