332 
from the nucleus to the anterior extremity. The nucleus was from 
3 '3 to 4’4 n in diameter, and was placed about //i from the anterior 
extremity and 4// from the posterior extremity. 
One and two constrictions in these forms were observed, showing 
the method of progression described in fresh specimens (Plate 
XXVIII, figs. 70, 71). In a few specimens the nucleus had apparently 
divided into two, and the halves were attached by a red line 
(Plate XXVIII, figs. 68, 69). 
Some of these forms were encysted, both in erythrocytes and free 
in the serum. Such encysted forms often had a small amount of 
red-staining excretion at both ends (Plate XXVIII, figs. 59, 60). 
The “ slender ” forms (Plate XXVIII, figs. 73, 74) were from 13 to 
15// long and I'l/z wide. The cytoplasm was light-staining and of a 
loose texture. The shorter or posterior end was very faint-staining 
and the extremity could be seen with difficulty. The longer or 
anterior end was a faint pink, which deepened towards the extremity. 
On both sides of the nucleus were areas staining the same as the 
cytoplasm of the erythrocytes. There were two, sometimes three, 
of these areas which were from o'6 to 17 n long. Near the posterior 
extremity there were sometimes from two to four or more red 
chromatin granules, and occasionally there were a few in the anterior 
part of the body. 1 he nucleus consisted of eight peripherally arranged 
chromatic granules, “ chromosomes,”* and one or two darker, central 
chromatic granules, “ karyosomes,” all connected by fine lines. In 
one instance (Plate XXVIII, fig. 73) a blue spiral line was found to run 
from one of the chromatic granules to the anterior extremity of the 
body. The nucleus was 2 '2/t long and was placed 9/1 from the 
anterior extremity, and 3*3/1 from the posterior extremity. This 
slender form may be present in the blood with the larger form, 
or it may be present in blood which has none of the larger forms. 
These slender ’ drepanidia penetrate the erythrocytes, then lose 
both ends, so that only the nucleus and a small amount of cytoplasm 
around it is left. The chromatic granules go to the side, and later 
they are gathered in a mass at one end of the body, with a few 
chromatic granules remaining outside the mass (Plate XXIX, fig. 76). 
1 he body of the parasite enlarges and at the extremity opposite the 
chromatin mass are several round clear spaces, which may or may 
in a nnrl'lT,! 1)6 lln ^ erstooci that the terms chromosomes and karyosomes are 
in a purely descriptive sense. : 
