DISEASES OF BLOOD AND BONE MARROW 111 
marrow. The latter may show a myeloid picture, but 
mononuclears without granules, with deeply staining 
nucleus and protoplasm, are usually more numerous ; two 
cases recently studied, one of tuberculosis and one of 
pneumonia with general congestion, had similar bone 
marrow — pale homogeneous red with distinct mono- 
nucleosis, more outspoken, however, in the former case. 
Pigment is not common in the avian marrow. 
The relation of the marrow to general conditions has 
been mentioned in the foregoing pages, but perhaps the 
following diagnoses will illustrate other connections seen 
among our records : 
Bactrian Camel {Cameliis hactrianus). — Hydatid dis- 
ease of lung and liver. Hemorrhagic enteritis. Atrophic 
bone marrow. Calcified areas in thyroid, 
American Gray Wolf {Canis mexicanus) . — Cretinoid. 
Hemorrhagic external pachymeningitis \\ith cranio- 
tabes. Secondary hyperplasia of thyroid with colloid. 
Chronic Ijonphatic hyperplasia. Chronic interstitial 
nephritis. Chronic enteritis. Osteogenesis imperfecta. 
Hemorrhagic bone marrow. Concentric hypertrophy and 
dilatation of heart. 
Myeloma, 
Perhaps, no pathological condition has given rise to 
more varied opinions than the tumor-like hypei-plasias of 
the bone marrow, growths resembling bone sarcoma with 
and without giant cells — myeloma, chloroma, pseudo- 
leucemia ossium and many others. In brief only two 
cases occur in our series which could be admitted to this 
category. There have been osteomata, but they were so 
clearly local tumors that they cannot be included in 
myeloid neoplasms that are assumed to be systemic in 
nature. Here is not the place to engage in a discussion of 
the correct classification and nomenclature since there 
are included only the aleucemic newgrowths usually 
assumed to originate from blood-making cells. The first 
