574 DISEASE IN WILD MAMMALS AND BIRDS 
loss of appetite is in large part due no doubt to the dis- 
comfort of che\\'ing and swallowing in the presence of an 
inflammatory^ mass in the neck. The eyes usually remain 
normal until quite late. No change in the character of 
the droppings is recorded. 
A slightly different course is followed by the cases 
that have the primary lesion in the " hare lip " and nose ; 
from these the masses along the jaw may be entirely 
missing. After an initial stage of '' running nose " with 
or without swelling of the upper lips and alse of the 
nose, the animal rapidly goes douTi hill, with dyspnoea, 
loss of flesh, perhaps loose stools, lusterless eyes and a 
" dead " coat, a series of signs indicative of a septicemic 
state not pronounced in the first variety; any form of this 
infection may however present course and pathology 
of a septicemic character. If the beast live long enough 
ulceration may appear on the upper lips or a large area of 
necrosis between them may be discovered. 
There have been in our series two cases, believed to be 
due to the same virus, which gave a picture of septice- 
mia with pulmonary localization; they will be discussed 
in detail later but are of interest here because they were 
not known to be sick until the day before their death. A 
similar failure to evince signs of sickness is found in 
the gastrointestinal cases, those with ulcerations in the 
stomach and perhaps an accompanying catarrhal intes- 
tinal inflammation. At most the report wall be that the 
specimen was '' off its feed." 
The signs of Kangaroo disease with exception of those 
applying directly to the nose and jaw are therefore very 
vagTie and one is limited to observation of the contour 
of the head and of the discharge from the nostrils. Be- 
cause of the indefi^nite nature of the earliest changes, 
the duration of the disease cannot be stated with accuracy 
but from the time that the swellings are perceptible it is 
not verv^ protracted if no treatment be given. Some cases 
die in four or five days while others may last up to three 
