THE STREPTOTHRICOSES 579 
tory tissue is not distinctive, except in so far that fibrosis 
enclosing pus pockets is peculiar to it. In softer tissue, 
like the liver, fibrosis is not so prominent, whereas diffuse 
and irregular spread is more pronounced. At the margin 
with the healthy tissue, reactive, that is resistant, inflam- 
mation is no more in evidence than within the tumor 
growth itself and as a matter of fact the tissues do not 
seem to put up a good fight against the spread of 
the inflammation. 
Histologically, aside from the finding of the strepto- 
thrix colonies, there is nothing distinctive, the peculiar 
expressions of the disease being most manifest in their 
gross characters. For the purpose of describing the 
pathological features, the cases have been divided into 
the necrotizing form around the jaw, a similar process 
in the stomach and liver, necrotic cervical cases followed 
by lung involvement, the nasal variety upon which pneu- 
monia succeeds and a septicemic form arising from any 
locality. Illustrative cases will be cited for each of these 
forms, a method of presenting the pathology thought to 
be superior to a general discussion. 
The first illustrative case is one localized in the 
tongue and pharyngeal wall; it is quoted because of its 
strict localization. 
Great Gray Kangaroo {Macropiis giganteus). Sick four days, tongue 
swollen so he could not eat. 
Diagnosis. — Necrotizing process of floor of mouth and pharyngeal 
wall, dilatation of heart, passive congestion of liver, acute diffuse 
nephritis, inflammatory edema of lungs. General condition good. Jaws 
and teeth negative. Floor of mouth firm in places, boggy in others, 
but generally infiltrated. Anterior two-thirds of tongue purple and 
green as if gangrenous. Root of tongue and adjacent floor of mouth 
yellowish, wet as if from recent coagulation necrosis. In the muscle 
of the tongue a line of demarkation is shown at end of hemon-hagic 
zone behind which muscle is fairly good. Sides of pharynx, palate, 
tonsillar region show superficial pseudomembranous inflammation and 
yellowish gray, wet infiltration of muscles. Epiglottis purple and 
swollen to twice normal size. Laryngeal mucosa deeply injected, swol- 
len and covered with tenacious gray mucus. Trachea and bronchi deeply 
injected and slimy. The lungs are uniformly deeply injected and along 
