THE STREPTOTHRICOSES 581 
the middle of the lesser curvature is an ulcer about 4 cm. across. The 
shelving edges are covered ^\4th apparently normal mucosa. The centre 
contains bloody pus and nodular masses of the submucosa extending 
in finger-like projections through the pus. At one point on the greater 
curvature there is a small pocket of pus on the sei'ous side which has 
not ulcerated through to the mucosa nor broken into the peritoneum. 
The large intestine is deep red and the follicles appear from the serosa 
as darker areas. On the mucus side the follicles have ulcerated, having 
a necrotic centre and shelving edges. The rest of the mucosa in the 
neighborhood is swollen and deep red. The colon mucosa is dry and 
the contents are hard, dry " baked " feces. The main pancreatic duct 
and the common bile duct form a thick, firm, cord-like mass running 
through the pancreas and enlarging the papilla of Vater into the duo- 
denum. All abdominal lymph nodes are large, fii'm and on section 
mottled with red areas. Culture from the liver abscess failed to grow. 
Histological section of lung shows moderate congestion, collapse of 
alveoli or their filling by edema, epithelial and small round cells. There 
seems to be no fibrin. This could be an early stage of pneumonia. 
Bronchi are for the most part negative, little peribronchial round cell 
infiltration. No streptothrix in two areas of round cell infiltration or 
in bronchi. Liver section shows a part of the liver destroyed by hemor- 
rhage, degeneration and necrosis. The abscess consists of necrotic matter 
surrounded by a zone of about equal numbers of mono- and polyuu- 
clears and around this a loose fibrocellular zone. Streptothrix abundant 
in the abscess. Lymph nodes show chronic inflammation and coagula- 
tion necrosis without abscess formation. No streptothrix in areas of 
necrosis. Kidney is very much congested with little or no damage to 
secreting parts. Spleen shows enormous congestion, moderate amount 
of pigmentation, connective tissue both trabeculse and through pulp 
increased, no areas of necrosis. In the stomach the mucous membrane 
shows slight cellular activity and some degeneration — this amounts to 
a true catarrhal gastritis especially in view of the submucous cellular 
infiltration and the granulation tissue which has separated the museu- 
laris and involved most of the connective tissue. The edge of the 
necrotic part begins abruptly, the mass of necrosis lying on an active 
fibrocellular submucous and muscular layer. Streptothrix can be seen 
at edge and in necrosis. 
Pneumonia originating either by inhalation or via the 
blood stream, is illustrated in two stages by the succeed- 
ing cases. The first history illustrates the pulmonary 
involvement as secondary to necrotic streptothricosis 
around the jaw and tongue while the second animal's 
disease began in the nose and related sinuses. These 
two protocols provide material for a discussion of two 
phases of the subject. 
