234 DISEASE IN WILD MAMMALS AND BIRDS 
may have been responsible for the pigmentation. Biliary 
cirrhosis occurred in two Carnivora, in both associated 
with enlarged spleen and nephritis. One showed jaundice 
and the other, \dth a huge liver from congestion and 
interstitial infiltration, had a small ascites. Fatty cir- 
rhosis was diagnosed in a raccoon but this is viewed mth 
some reservation because this animal easily stores fat 
and in this case it may not have been a part of the process. 
In none of the foregoing cases did parasitism enter into 
the causation of the change and I shall always specify 
when such a factor was probable. The only vascular 
cirrhosis in our records occurred in a Gray "Wolf incident 
to a longstanding myocarditis (Gray Wolf, Cauis lupus 
mexicanus, Myocarditis, Adenomatoid goitre, Chronic 
gastroenteritis. Vascular cirrhosis of liver, Subacute dif- 
fuse nephritis. Edema of lungs, pericardium, and peri- 
toneum). Two examples of perilobular fibrosis appeared 
in this order, a raccoon {Procyon lotor) and a paradoxure 
{Trichosurus vulpecidar vulpecular). The only note- 
worthy feature was, in the former, a very marked biliary 
stasis on the lobular margins and in the connective tissue ; 
this animal was not jaundiced. 
Ungulata are normally well supplied wdth definite 
interlobular strands which, in a few varieties, completely 
encircle the lobule but always show as clear fibrous septa 
going out from the portal areas. This richness of con- 
nective tissue renders more difficult a decision of increase 
so that unequivocal degenerations and regenerations 
with inflammatory changes have been demanded as cri- 
teria for cirrhosis. It has been recognized that cattle get 
a definite increase in their interstitial tissue without 
serious reaction in the parenclwma. With the knowledge 
of these facts in mind it has been possible to detect two 
distinct portal cirrhoses, two biliary cirrhoses and three 
perilobular fibroses. It is however e\'ident by exaraining 
the rest of the autopsy notes that the chronic inflam- 
mations have had with one exception, little influence on 
