314 DISEASE IN WILD MAMMALS AND BIRDS 
tion. Chronic change was observed in these bodies on two 
occasions, and prostatic hyperplasia, commonly called 
hypertrophy, was seen thrice. The mammalian prostatic 
area is known to become overfilled with secretion and to 
be affected by inflammation when it is not discharged. 
This occurred in a wood rat {Xeotoma pennsylvanica) 
and a wild boar {Sus scrofa), the former having the 
condition so marked that prostate and seminal vesicles 
were swollen backward into the pelvis like a tumor. His- 
tologically one finds in these conditions an engorgement 
of the glandular and ductal spaces with a mucoid sub- 
stance and a mild round and plasma cell infiltrate in the 
connective tissue ; there are no marked evidences of 
active inflammation. The testes were not abnormal in 
these cases. 
The three cases of '^ hypertrophy" of the prostate are 
worthy of separate record. 
Indian Paradoxure (Paradoxiirus niger) the prostate is greatly 
enlarged, of pale orange color, soft and does not exude pus on section 
or pressure. 
Common Opossum {Didelphys virginiana) The prostate is 
enlarged, soft, gray j'^ellow. Urethra contains a little gray mucus but 
seems patulous. Seminal vesicles negative. 
Rhesus Macaque (Macacus rhesus). Glandular hyperplasia of 
prostate. The bladder is collapsed. The opening of the urethra is 
occupied by a firm, friable yellow-white cast of matter apparently in- 
spissated semen. Urethral mucous membrane normal. Prostate is 7 x 
4.5 X 3 cm. firm, resilient, dull purple-gray, capsule negative. Section 
shows normal lobulations containing apparently normal secretion. Vasa 
negative. Testes negative. Microscopic section of prostate shows acini 
of various sizes lined by a single layer of tall vacuolated cells with 
nucleus at the bottom. Cells probably nowhere reduplicated. Acini 
nowhere grossly atypical but everywhere hyperplastic and dilated irregu- 
larly. Mass is adenomatous in general increase but no part is truly 
neoplastic. Interstitial tissue rather less than normal proportion- 
ately. No " amyloid " bodies. 
Still another case of accessory sex gland enlargement 
was found in a Ring-tailed Lemur {Lemur catta), this 
time, however, with more suggestion of a neoplastic 
change. The prostate of the lemur is normally large, 
