THE DUCTLESS GLANDS 339 
dropped out and partly disturbed by overgrowth of con- 
nective tissue. This connective tissue is quite prominent 
in the medulla where it is surely increased although it is 
made more prominent by absence of cells, some of which 
have been degenerated and some dislodged. ' ' A Japanese 
Macaque {Macacus fuscatus) after drooping three weeks 
presented at autopsy the following numerous lesions : 
anemia, chronic atrophic gastritis, atrophy of heart muscle 
with regeneration, hemosiderin pigmentation of liver, 
perilobular fibrosis of liver, chronic diffuse nephritis 
(subcapsular type), congestion of spleen, fibrillar fibrosis 
of spleen, hemosiderin pigmentation of spleen, local 
amyloid infiltration of spleen, calcareous infiltration in 
medulla of adrenal. Grossly the adrenal showed a thick, 
orange yellow cortex and small solid, brown medulla. 
''Histologically the organ appears normal in all respects 
save for the presence of a few small irregular areas of 
calcification in the medulla. These occur apart from any 
recognizable necrotic or fibrous areas. In one place one 
appears to lie within the lumen of a blood vessel. No 
fibroses or special congestions found anywhere in the 
organ and cells show normal details and normal nmnbers 
of vacuoles." 
A California hair seal (Zalophus calif ornianus) 
which had been refusing food and having loose stools 
for about ten days presented after death the fol- 
lowing diagnosis : Hypernephroma of adrenal, chronic 
hypertrophic enteritis mth acute exacerbation, hemor- 
rhagic splenitis, passive congestion of liver, congestion 
and edema of lungs with catarrhal pneumonia, acute 
fibrinous pericarditis, chronic lymphadenitis, chronic 
interstitial nephritis. His right adrenal seemed about 
normal, being 5 x 2 x 1 cm. with a narrow, dull 
yellow cortex and a large mottled gray brown medulla. 
The left one was 5x3x1 cm. The upper pole is 
swollen and contains in its centre a spherical tume- 
