342 DISEASE IN WILD MAMMALS AND BIRDS 
adrenal, when judged purely by its histology but a second- 
ary tumor in the lung displayed the more familiar picture 
of large vacuolated cells as seen in hypernephroma. The 
diagnosis follows: '* Scirrhous adenocarcinoma of 
adrenals, secondary carcinoma of lymph glands, second- 
ary hypernephroma of lung, secondary carcinoma of 
diaphragm, acute mucopurulent bronchitis, acute catarrhal 
enteritis, chronic diffuse fibrous cholecystitis, choleli- 
thiasis, slight acute interstitial pancreatitis, follicular 
hyperplasia of spleen with fibrosis, hydrothorax, 
hydropericardium, chronic hypertrophic osteoperiostitis, 
encysted trichina in diaphragm, fatty infiltration of 
diaphragm, chronic diffuse nephritis, chronic productive 
Ij-mphadenitis, pigmentation of lymph gland. Both 
adrenals are smaller than normal, of woodeny consist- 
ency, the pale cortex and medulla are poorly separated 
from each other. The cut surface shows gray white and 
taA\Tiy mottling and occasional calcareous points. Histo- 
logical section shows an extra capsule of fibrous tissue 
containing highly distended veins; the lining contains 
masses of tumor cells, many of which are necrotic. It is 
distinctly denser in type than normal and more abundant 
in places sho\\'ing a proceeding fibrosis. Parenchyma 
shows but few irregular islands containing non-neoplastic 
cells, some of which are highly vacuolated, others are not. 
Interstitial tissues in peripheral parts are often grown 
together ^viih the deeper portion where are intermixed 
tumor areas. The latter consist of small round acini of 
variable size Uned by cells of active type. Nuclei are 
large and hyperchromatic, cytoplasm broad and disinte- 
grating. Parts show necrosis and hemorrhage. Upon 
search transitionals from non-neoplastic to neoplastic 
cells can be discovered in same fasciculus." 
