404 DISEASE IN WILD MAMMALS AND BIRDS 
good as any for his age. He was never known to have anything wrong 
with him until on the morning of June 3, 191-i, Avhen he was found on 
the bottom of the cage in the monkey house. He had clenched hands 
and feet, jaws tightly closed, lips drawn back, eyes staring and glassy, 
with convulsive shaking of the extremities. At intervals he would 
become limp, vnth fists still clenched, and mth only occasional jerks in 
the extremities. This would last about a minute, and then convulsive 
movements would be resumed. The entire " fit " lasted about ten 
minutes. He was immediately removed from the large cage in the 
monkey house to a small one in the back room of the laboratory. When 
put in the small cage he staggered as if dazed, and groped about 
apparently blind. He never recovered his sight entirely, but at times 
seemed to see better than at others. He was not seen in a " fit " in the 
laboratory. On June 24th, a small piece of banana was offered by a 
person who stood directly in the sunlight. The monkey came to the 
front of the cage, reached out and grasped very firmly the thumb of 
the hand holding the banana but did not take the banana although he 
very plainly wanted it. The banana was thrown into the cage, hitting 
the monkey on the back. He turned very quickly, then smelled over 
the floor of the cage until he found the banana. On June 30th, he 
was examined by Doctor Langdon and the following condition was noted : 
" Pupils react to the light of the ophthalmoscope. Optic discs are 
normal. Arteries possibly a little small. No other fundus changes." 
On July 1, a cloudy day, he was laid facing a window. A coat sleeve 
Avas laid over his eyes for a minute and then quickly removed. His 
pupils were seen to react slowly but distinctly to the light. His gaze 
Avould not follow a finger moved in front of his eyes. When put back 
in the cage he climbed up on the wire at the back and then tried to 
climb the plain sheet-iron side. He gn^-oped and felt for a support and 
then fell. This he did several times. About August 1, when the eyes 
were examined, there seemed to be more visual perception and very dis- 
tinctly prompter pupillary reflex, which condition remained about the 
same when examined October 1. He died October 10, 1914, of a com- 
pound fracture of the right femur inflicted by a monkey in the ad- 
joining cage. 
At autopsy the viscera appeared normal throughout. The animal 
was fairly well nourished. There was about 5 cc. clear, pale yellow fluid 
under the dura. It escaped upon removal of the brain. There were 
adhesions of the dura over the temporal lobe (inferior surface), poste- 
rior and external to the optic tract, so firm as to remove some periosteum 
and superficial bone. Rest of dura seemed normal. 
Examination of the brain. Sections were made from different parts 
of the cerebral cortex, all of which were more or less alike. There was 
swelling of the endothelium of the pial lymph spaces, with some separa- 
tion of the fibres of the pia itself which extended into the sulci. The 
perivascular lymph spaces of the larger arteries of the cortex were 
dilated, and the adjacent cerebral tissue was edematous. A well marked 
endothelial swelling and hyperplasia affected a number of the arteries 
