Apr. 15, , 9 ,i Carbon Tetrachlorid for the Removal of Worms 169 
an efficacy of 100 per cent; the total for the series of 6 infested dogs was 
17 hookworms passed and 83 left, or 17 per cent for chloroform in dosage 
of 0.1 to 2 m. p. k. administered in castor oil. Chloroform administered 
in soft capsules in 15-minim doses on the first, fourth, sixth, and eighth 
days of an experiment removed no hookworms and left 6, an efficacy of 
o per cent; administered in soft capsules at the rate of 0.3 m. p. k. it 
removed no hookworms and left 4, an efficacy of o per cent. 
The totals for all the foregoing tests with chloroform show that it 
removed 491 hookworms and left 445, an efficacy of 52 per cent. 
CHENOPODIUM 
Hall and Foster (9) found that chenopodium in doses of 0.3 m. p. k. in 
castor oil administered to 8 dogs removed about 25 per cent of their 
hookworms; in doses of 0.2 m. p. k. in capsules administered to 8 dogs 
daily for 3 successive days it was ineffective against hookworms. 
Hall and Hamilton (jo) found that the heavy fractions of oil of cheno¬ 
podium, those distilling over at the higher range of temperature, 
administered in doses of 0.1 m. p. k. to 5 infested dogs removed no hook¬ 
worms and left 68, an efficacy of o per cent; the light fractions adminis¬ 
tered in doses of 0.1 m. p. k. to 2 infested dogs removed 1 hookworm 
and left 76, an efficacy of little over 1 per cent. 
Hall (<8, pt. /), using chenopodium in repeated doses, found that 111 
2-minim doses daily for 18 days given to 3 infested dogs it removed 12 
hookworms and left 9, an efficacy of 57 per cent; in 5-minim doses daily 
for 12 days given to 2 dogs it removed 1 hookworm and left none, an 
efficacy of 100 per cent; in 5-minim doses given 4 times in 1 week to 1 
dog it removed 3 hookworms and left 11, an efficacy of 21 per cent; in 
doses of 0.5 m. p. k. daily on 2 successive days to 1 dog it removed 5 
hookworms and left 16, an efficacy of 24 per cent; in io-iniuim doses 
at 1-hour or %-hour intervals for a total of 3 doses to 4 dogs it removed 
10 hookworms and left 24, an efficacy of 3° P er cent; in 5-minim doses 
at 1-hour intervals for a total of 3 doses it removed 1 hookworm and 
left none, an efficacy of 100 per cent. The totals show that, in repeated 
doses as given, chenopodium removed 32 hookworms and left 60, an 
effieacv of 35 per cent. 
Hall and Wigdor (11), using the soft, or soluble elastic, capsules, 
found that chenopodium at the rate of 0.1 m. p. k. given to 7 infested 
dogs removed 23 hookworms and left 8, an efficacy of 74 per cent; using 
hard capsules instead of soft, chenopodium at the rate of 0.1 ni. p. k. 
given to 2 infested dogs removed no hookworms and left 16, an efficacy 
of o per cent. 
Hall (8, pt. VI), using enteric-coated capsules of chenopodium in 
single doses of 10 to 20 minims, found that it removed 4 hookworms and 
left 6, an efficacy of 40 per cent. 
