35 
This patient must have received her infection some time during 
1900. The conclusions that she has overcome the infection and that 
trypanosomiasis in man is not necessarily fatal are, it seems to me, 
justifiable. 
Dr. Broden has published his notes of this case. 
II. --H. K. This was Forde’s original case in which Trypanosoma 
gambiense was first definitely recognised (and for the first time in 
human pathology) by Dutton. It has been fully described by Dutton 
in the publications of the Liverpool School of Tropical Medicine, 
and elsewhere by Forde. I mention it here as it constituted my first 
conscious experience of trypanosomiasis in man. I saw the case in 
August, 1902, and had the clinical points of the disease demonstrated 
to me by Dutton. It was from what I saw on that occasion that I 
was enabled to recognise clinically the disease in the next case. The 
medicinal treatment consisted principally in the administration of 
arsenic, quinine and urotropin. The patient died the following 
January, about one year and eight months after the presumed date 
of infection. 
III. —Mrs. S. was seen by me for the first time in October, 1902. 
She presented the usual clinical picture of trypanosomiasis, and the 
parasite was found in her blood. The case has already been fully 
recorded in the British Medical Journal of May 30th and December 
6th, 1903, and elsewhere. I may mention here that the first 
indication of the disease occurred in August, 1901, supervening, 
apparently, on an insect bite on the leg. The patient died of sleeping 
sickness on November 26th, 1903, two years and three months after 
infection. The treatment included arsenic, quinine, methylene blue, 
and many other drugs, but not atoxyl. 
IV. —w. z., an engineer on one of the lake steamers in Uganda, 
came under my observation on October 9th, 1905. His story was 
that early in the year he broke his leg; that on this account and 
because he suffered from fever he had been in hospital in Uganda for 
a considerable time; and that trypanosomes having been found in 
his blood he was invalided on July 26th. On arrival he went to his 
home in Scotland, where, with the exception of two days’ fever, he 
kept well and put on flesh. He stated, however, that he had suffered 
from dull pains in his legs and that once he had a swelling in his 
left foot. 
