36 
When I saw him, there was a well-marked drcinate cr)'thcma on 
his chest, and the cervical and inguinal lymphatic glands were 
enlarged. On examination of the blood trypanosomes were found 
His pulse was rapid -io8- his spleen palpable, knee jerks 
exaggerated, slight right ankle clonus. He complained that he felt 
weak, and also of subjective symptoms of numbness in the legs. 
Otherwise he appeared to be well. BIrjod count 4 , 00 (\ck 30 . He was 
sent to hospital. 
During his stay there he had a malarial attack and benign tertian 
parasites were found in his blood. Quinine quickly got rid of this 
infection. He also developed a specific periostitis which Yielded to 
potassium iodide. 
From October i8th, 1905. to January 25th, 190O. he was treated 
by trypanroth and, later, by trypanroth and arsenious acid, the latter 
hypodermically. The erythema persisted, however, or, if it faded for 
a time, would again return. Occasionally the erythematous spots 
gave one the impression that they were slightly oedematous. 
Trypanosomes were also occasionally found in the blood, but gland 
puncture, wliich was twice practised, was negative. The temperature, 
except during the malarial attack, remained normal throughout. 
The skin and urine became deeply stained by the trypanroth. 
On January 26th, albumin having appeared in the urine, the 
trypanroth and arsenious acid were stopped. On Februar>- 5th 
treatment by atoxyl injections was commenced. Beginning with one 
gram twice a week it was gradually raised to four grains twice a 
week, at which dose it was continued till the spring of 1907 
Very soon after commencing; the atoxyl he became conscious of 
an improvement m h.s general health. The erythema no longer 
bowed Itself on the trunk, and for over six weeks, notwithstandfng 
I bCd^L^ ““Id not be found in 
■n Uganda, he came to London during “PP™"!"'™' 
blood was again carefully examined for Ln u 
found. However, a monkey injected fa Jh 
developed trypanosomiasis and Ld ^ ^ "-ith his blood 
