44 
The last dose of parafuchsin was taken on October 17th. Ten 
days later there was a rise of temperature, and once more the 
parasites appeared. About this time the patient apparently got a 
chill while salmon fishing and there was some rise of temperature, 
which was repeated on November 1st and 2n(l. when a very large 
influx of trypanosomes was noted 
Sodio^tartrate of antimony.--On November 8th I administered a 
hypodermic injection of sodio-tartrate of antimony (kindly supplied 
by Mr. Plimmer) ‘ a grain, and foliowcti it up witli injections of 1. 
2, and 2 grains on the loth, nth. 12th and 15th respectively. 
There was no nausea, intestinal disturbance, or albuminuria following 
the injections, but the local pain and irritation were great. The 
parts became puffy, then hard, then fluctuating. One swelling, which 
a ecome very tense and discoloured, and seemed as if about to 
rupture, I .ncised About un ounce of dark sanious fluid escaped, 
wound The slough took a fortnight to come away, and the wound 
Twlmn r a very long tin.e to heal. The other 
tlTe inlcf pan. consequent on 
towardf r' "'orphia. It would subside 
forenoon bu?'”^l.“? comparatively m abeyance during the 
s~d;r.n ‘r trT “P being most 
,. , ^ night, rendering slcen imDot;«sihlp T'l 
z:v;rs:'- "r "S 
given rLfeentlte‘rg\'l.s"(i‘to T ptr" ""n'T 
antimony was quite a*; ' f 1 ^ cent) the weaker solution of 
-tramuscular injection. th^gL 
swelling than subcutaneous injection ^ ^ 
When it became evident tha tv ^ • 
was impracticable, the drug was eiven '"J^ction of antimony 
two grains a day diluted in twn rs ^ mouth to the extent of 
with three gra^n doslforatoxyr IsZZZ" "/■ 
nausea or irritation of any sort. ^ continued. It causes no 
Up to the date of this note there has K 
The patient is leading an active rT . , °f f«'er. 
^ hfe and is feeling perfectly 
