5 
specimens of the blood, and these were exceedingly torpid On the 
21st the haematozoa were entirely absent, and from this date the 
animal appeared unable to throw off the effect which the return of 
the haematozoon had given rise to, and he gradually became weaker, 
and died on the 29th of July, although the haematozoa were absent 
during the last nine days. 
‘ It was decided in this case to try again the effect of the mixed 
Cinchona alkaloids and Arsenic on the haematozoon, as it had shown 
promise of efficacy in that of Horse No. LXV, in which case after a 
short exhibition of the drugs, the haematozoon was kept in subjection 
for a period of twenty-seven days. Consequently as a fresh trial was 
resolved upon, the animal was first put upon small doses, beginning 
with one drachm of the Alkaloids and four grains of Arsenic, given in 
the form of the Liq. arsenicalis. On the morning following the first 
dose, the temperature was found to have fallen over a degree, and 
the haematozoon was absent from the blood, the temperature 
remained low, and the organism absent for the next five days, during 
which period two doses of the medicine were administered daily. 
‘ On reference to the Chart, it will be seen that on the ninth day 
of the disease the haematozoon again appeared in the blood, 
consequently on the tenth the doses of Alkaloids and Arsenic were 
increased to one and a half drachms and five grains respectively; 
these were continued for a period of eight days, during which time 
the haematozoon varied in numbers between few and very numerous. 
On the eighteenth day of the disease a further increase in the doses 
was agreed upon, and during the next four days they were put up to 
Alkaloids two and a half drachms and Arsenic grains vi, and for the 
latter half of this period the organism was absent from the blood, but 
re-appeared on the twenty-second day, and remained on the twenty- 
third at few. On the former date the Alkaloids were increased to 
three drachms, and the Arsenic to grains viii, and from the twenty- 
third to the thirty-fifth day of the disease, on which latter date the 
animal succumbed, the haematozoon was entirely absent from the 
blood. During the thirty-two days the animal was under treatment, 
three hundred and fifty-five grains of Arsenic in the form of Liquor 
arsenicalis, and one hundred and fifty-four and a half drachms of the 
mixed Cinchona alkaloids were administered.’ 
He further quotes the case of an animal belonging to the Bombay 
