lOQ 
parasite in the sheep. The tijne at our disposal, however, was not 
sufficient for a careful study of the question, and our observations 
were without definite results. 
No special symptoms were noted. During the course of the 
disease a rapid emaciation took place, but all the animals were alive 
when the work was concluded at the end of September. Each access 
of fever was manifested clinically by the weakness, depression and 
excessive lachrymation shown by the animal. Oedema was not seen 
in either these animals or goats. 
Parasites were never numerous : on one occasion only were as 
many as six to a field seen. The number, however, depends upon 
the period in the onset or decline of the paroxysm at which the 
routine examination happened to be made. 
Case No. XXXVI.—An aged ram, fat-tailed variety, purchased locally, but 
probably imported from the South. August 7th, inoculated subcutaneously with 
S'o c.c. citrated blood of XXV. The temperature became irregular on the 5th, and 
organisms were first seen on the eighth day, August 15th. For the first fourteen days 
the paroxysms were tertian in type, afterwards becoming less regular and approach¬ 
ing the quartan type. Emaciation was rapid, but the animal was still alive on 
November 20th, and organisms were present, (vide chart iii.) 
Case No. LVI. — Two-year-old female. September 3rd, inoculated sub¬ 
cutaneously with i-o c.c. citrated blood of XLll. Organisms first seen on the 7th 
day, September 10th, and the initial thermal paroxysm occurred during the night 
of the nth. On the evenings of September 14th, i6th, i8th, 20th, 22nd, and 24th, the 
temperature exceeded 106° F., and on the a8th it reached 107°. During the twenty- 
one days of observed disease the type was essentially the same as in No. XXXVI, 
the chart of which is reproduced. ’ 
Case No. XXXIII.-Male, aged one year. Between August igfh and September 
2nd this animal had .shown what we regard as T. vivax with which it had been 
inoculated. After this latter date the temperature remained about normal and 
trypanosomes were not seen. 
September 17th, received subcutaneously 0-5 c.c. heart blood of guinea-pig, 
Case XLVI, dead with T. dimorfkon. The temperature was faily constant until 
the 27th, when it commenced to rise. On the 28th, the nth day, T. dimorthon was 
seen, the first paroxysm occurring the same day, the second (io7-2'>) on the evening 
of the 30th, the last day of observation, (vide chart ix.) 
4 - Goats. These animals, as already stated, are regarded as 
immune. Three readily took infection with T. dimorphon after an 
incubative period of seven to twelve days. The disease is of 
essentially the same type as that in sheep, viz., a tertian and quartan 
febrile reaction and a concomitant influx of organisms into the 
peripheral circulation. No special symptoms were observed. 
Case No. XXXV.—Male, aged one year. August 7th. Inoculated under the 
skin with 5-0 c.c. citrated blood of XXV. The temperature became irregular until 
organisms appeared on the seventh day, August 14th. During the seven weeks 
