r 
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3. Sheep. Four sheep were inoculated with this trypanosome, 
and in three the organism reappeared. Only one, a small weakly 
animal, died during the period they were under observation ; and from 
an examination of the temperature charts and of the animals 
themselves, it would seem that recovery may occur naturally, though, 
of course, we were unable to prove this in the time. The inoculation 
period in two cases was seven days. Trypanosomes were always 
scanty, rarely exceeding four to a cover-glass, their activity being as 
great as in cattle. This fact may account for the irregularity of their 
detection and the apparent lack of relationship between their 
occurrence and a thermal rise. The picture presented by the 
temperature chart differs absolutely from that following inoculation 
with T. dimorphon. The temperature rose between the fourth and 
seventh days, and fell again a few days later, and remained irregular 
for two or three weeks. There was no periodic exacerbation of a 
tertian or quartan type. 
Case No. X.—A small ‘weedy’ animal of five months old. July nth, 
inoculated subcutaneously with s’o c.c. blood direct from Case No. VIII. The 
temperature rose on the fourth day and continued elevated for the ten days it was 
under observation at the first camp. Mr. Johnson, on whose farm the second camp 
was established, kindly visited the animal nine days later and made films in which 
trypanosomes were detected. It was then weak, and the native in charge said it 
had been sick for three days. It was carried in, 22 miles, to our new camp and 
died almost immediately on arrival. 
Post-mortem . — Trypanosomes were not found in the blood or gland juice. 
Visible mucous membranes pale, those of the conjunctivae showing a few 
petechiae. The subcutaneous lymphatic glands were enlarged, those of the 
mesentery being also haemorrhagic. There was no excess of fluid in the body 
cavities. Small petechiae studded the pleurae and pericardium. The spleen was 
not enlarged, its cap-sule was firm and showed a few petechiae. The liver and 
kidneys appeared normal. Neither intestinal parasites, nor D. he-paticum were 
found to account for the debilitated state at the time of inoculation. Two specimens 
of Cysticersus tenuicollis were present in the mesentery. 
Case No. XXXIII. — A healthy sheep aged one year. August 7th, inoculated 
subcutaneously with i-o c.c. citrated blood of IX. The temperature rose to 105-2'’ 
on the morning of the sixth day and organisms were seen the next morning. During 
the succeeding six weeks the temperature was four times above 105°, and 
tryi)anosomes were seen on eleven occasions. After September and the temperature 
remained about normal and parasites were not observed. On September 17th it 
was inoculated with T. dimorphon. (vide antea chart ix.l 
Case No. XXXIX. — A healthy sheep aged one year. August gth, inoculated 
under the .skin with i-o c.c. blood direct from goat, Case XI. Trypanosomes 
appeared on the seventh day, and for the next three weeks were fairly constantly 
present, but during the last three and a half week.s of observation they were only 
seen seven times. The temperature rose on the sixth day, and during the ensuing 
forty days of disease was similar to that of bovine piroplasmosis in India. 
