210 
characteristic trypanosome form. Tiie nuclei occupy a more or less 
central position. The body of the cell is short (fig. 28), or actually 
round (fig^. 3 1), and the long delicate flagellum is quite free. WTien 
such forms are elongated, as in fig. 2;, the flagellum and the extra- 
nuclear centrosomes lie together on one side of the nucleus, and the 
flagellum passes away from the vicinity of the extra-nucleai 
centrosome in an opposite direction 
. . - liioi llic 1IU1.1CU^ 
arising from the ultimate breaking up of the multi-nucleated masses 
are thus seen to possess all the morphological characteristics of the 
latent bodies, which are produced after the corresponding cycle of 
internal changes in the case of T. gambiense and T. equiferdum. The 
deiivatives of the multi-nucleated masses in T. lewisi thus correspond 
to the latent bodies of T. gambiense and T. equiperdum. In T.lewisi, 
however, the subsequent history of the latent bodies is far more easy 
to follow than in any case which we have hitherto been acquainted. 
T. lewisi in this respect constituting an admirable example for the 
further study of this important phase, which is less easy to follow in 
the development of the pathogenetic forms to which we have referred. 
The changes which succeed in the small flagellated forms or latent 
bodies of T. lewisi are essentially similar to the transformation of the 
atent bodies of T. gainbiense into the ordinary trypanosome form. 
The latent body elongates, the flagellum at first passing directly away 
from the surface of the body and in a direction opposite to that in 
1C the nucleus lies in respect to the extra-nuclear centrosome 
5 extra-nuclear cenfrosome migrates to one 
o t e cell body (fig, 32), and the flagellum is apparently dra^Ti 
over the surface of the body after it. This portion of the flagellnm 
o'f th attached to the cell forms, as it were, the ‘Anlagen' 
c-rr. 1^ « “re undulating membrane. The further development is 
P ) e ody elongating and enlarging into the ordinary 
trypanosome shape, as in figs. 33-38. When the form of small try- 
the represented in fig. 38. has been assumed, 
thronabT'''” be seen in figs. 34 - 3 /. 
back a • growth and further fissions gradually pass 
InTvfl description sTarted (fig- .)■ 
historv nf foregoing observ'ations upon the lif^ 
is th7oh ■ * “lost striking biological feature which emerges 
the obvious similarity that exists between the successive phases 
