326 
Faeces 
Date of Injection 
Amount Injected 
Date of Collecting 
Arsenic Recovereii 
12.3.08 
2 gm. Atoxyl 
13.3.08 
4 % 
16.3.08 
2 gm. Atoxyd 
17.3.08 
2% 
19.3.08 
2 gm. Atoxyl 
20.3.08 
5 % 
The chemical 
details of this work will be published shortly. 
Atoxyl has been found to bC'Secreted in the urine, as: — 
(1) p-amino-phenyl-arsenious acid; 
(2) p-oxy-phenyl-arsenious acid; 
(3) Arsyl-oxy-carbonyl. 
The presence of this third compound in the urine is of practical 
interest, in so far as its formation can only be explained by assuming 
that Atoxyl is acetylated in the organism, and afterwards the 
p-amino-phenyl-arsenious acid is transformed into Arsyl-oxy- 
carbonyl. Similar observations^ have been made on the secretion 
of p-toluidine, in which case Methyl-oxy-carbonyl is formed. It is 
quite possible that this may explain the fact that acetylated Atoxyl 
IS less toxic than Atoxyl. 
arsenic, anilin was found to be present, only in the faeces. 
Ihe faeces were treated with alkali, and steam passed through the 
mixture. The condensed steam gave distinctly, with bleaching 
powder, Hoffmann’s reaction. 
With regard to the distribution of Atoxyl in the organism, it has 
been shown by different authors that arsenic is deposed in all organs 
to a greater or lesser extent. J. Magalhaes 4 states that Atoxyl does 
statemenTh We have attempted to verify his 
withd r cerebro-spinal fluid of infected donkeys 
whhdrawn at d.lferent intervals after the last admin.stration of the 
