Extracts from British and Foreign Journals. 
RESULTS OE EXPERIMENTS ON PYAEMIA. 
Dr. Burdon Sanderson delivered an address on this 
subject. He began by relating his first experiments as to 
the effect of inoculating the lower animals with pyaemic 
liquids. In the autumn of 1867 he injected the purulent 
liquid contained in the ankle-joint of a patient, who had died 
a few hours before with metastatic abscesses, general suppu¬ 
rative arthritis, and intense septicaemia, under the skin in a 
dog and two guinea-pigs. The two guinea-pigs died within 
short periods (fifteen and twenty days), and exhibited symp¬ 
toms of great intensit}^ Both had metastatic abscesses; 
but in one the lungs were already beset with minute nodules, 
resembling miliary tubercles. The dog lived seven w r eeks. 
In this case there were no secondary abscesses, but miliary 
tubercles of the liver and spleen. From one of the guinea- 
pigs, two others w T ere inoculated, of which one died of pyaemic 
subcutaneous abscesses, without visceral disease ; the other, 
which lived longer, had no abscesses, but tuberculous disease 
of the lungs. During the same winter, other experiments 
of the same kind were made, all of which seemed to show 
that, by the inoculation of pyaemic products, two sets of 
lesions might be produced : as an immediate result, metastatic 
abscesses, accompanied by a general typhoid state, w’hich was 
often fatal; as an ulterior result, either disseminated nodules, 
at first hard, but afterwards becoming caseous at their centres, 
or interstitial induration—both forms of lesion having their 
seat chiefly in the lungs, spleen, and liver, but also occurring 
in other viscera. 
Having stated these facts, which he said had even in 1868 
led him to regard it as probable that the two forms of infec¬ 
tive lesions—the tuberculous and the pyaemic—were con¬ 
nected together etiologically and genetically, he referred to 
another fact w ? hich resulted from experiments made in 1871, 
as to the existence of bacteria in animal liquids, and the 
circumstances w^hich determined their occurrence. These 
experiments had shown that, w r hereas bacteria could not be 
show n to be present either actually or in germ in the healthy 
liquids or tissues, or in the products of healthy inflammation, 
they were present potentially in pyaemic liquids—that is to 
say, that, whereas ordinary pus could be kept for days or even 
weeks free from bacteria, provided the precautions against 
