I 
Facts and observations. 
Facts and Observations. 
Worms in Sheep. —The Pastoral Register , Australian 
paper, regrets to hear that the plague of worms in sheep has 
again been officially reported. The details of the nature of 
the complaints are not satisfactory enough to justify the 
assumption that the disease has appeared in as virulent a 
form as last year, and, pending further particulars, we are 
not prepared to say that the disease under notice is pre¬ 
valent. 
Influence of Dr. Wright’s Morphine Compounds 
on the Animal Body. —Some experiments on this subject 
were carried out by Dr. Reginald Stocker, Pathologist to St. 
Mary’s Hospital, and are of interest. He says that doses of 
1 decigramme of the compound C 68 H 81 IN 4 O 10 ,4H [ from 
codeia, and of the similar compound from morphia, were 
given to an an adult terrier by the mouth without producing 
any perceptible effect whatever; when the dose was increased 
to 3 decigrammes, in each case repeated defsecation in the 
course of a few hours was produced, the stools being more 
loose than ordinarily and frequently of a dark greenish 
colour; no other symptom was noticeable, and no appreci¬ 
able difference in the action of the two compounds was 
perceptible. Doses of 5 decigrammes of the compound 
C fi8 H 82 I 2 N 4 O 10 , 4HI from each of these sources were given to 
the same dog by the mouth, with the result of producing 
similar repeated defaecation in the course of two or three 
hours; the sole difference discernible between these and the 
former experiments being that the effect was produced some¬ 
what sooner, and was of longer continuance in the latter 
cases, a result probably produced solely by the larger dose. 
No material differences were observed between the codeia 
and morphia derivative. The same dog was employed 
throughout, two or three days being allowed to intervene 
between each experiment, so that the animal had recovered 
from the effects of a former dose before the administration of 
another.— Proceedings of the Royal Society, April, 1872. 
Bust of Dr. B. W. Richardson, F.R.S.—Mr. Davis, 
the sculptor, has completed a bust of Dr. B. W. Richardson, 
F.R.S. The likeness is admirable, and we trust that copies 
will be taken of it—say by the autotype process—so as to 
place within the reach of the profession the representation 
of one to whom medical science is under so many obligations. 
xlv. 37 
