610 
EXPERIMENTS WITH CARBOLIC ACID. 
scarring, which to the experienced eye is quite a sufficient 
tell-tale as to the nature of the disease. The cicatrices on 
the extremities are of a warty or horny nature, and are con¬ 
tinually giving off flakes of semi-horny material, whilst those 
on the body consist of a thin black pellicle of delicate tissue, 
slightly corrugated on its surface, and readily ruptured, in 
fact, presenting appearances like the cicatrices produced after 
the healing of a burnt wound. The term bursatie is applied 
indiscriminately to all sores, more or less, without reference 
to their benign or malignant nature ; but I conceive that 
true bursatie has three distinct forms or stages. 
(:To be continued .) 
EXPERIMENTS WITH CARBOLIC ACID. 
By P. Cullen, M.D., Calcutta. 
June 1st, at 7.27 a.m., 3 SS of carbolic acid was given to a 
little dog; in one minute he was a good deal agitated, and 
moved about in jumps, carrying his hind legs under him. 
In three minutes he lay down, got up again and staggered 
about a good deal. In five minutes *ij infusion of valerian 
(Pharmacopoeia strength) was given to him, after which he 
fell down, lay quiet for one minute, then got up and sat on 
haunches. In nine minutes he sank into a half sitting and 
half lying posture, and was panting a good deal, and for 
some time kept changing his position, sometimes sitting, and 
sometimes lying down. In fifteen minutes the symptoms 
began to decrease. At twenty minutes after the dose, a little 
cold water was sprinkled on his head, when he got up, and was 
enabled to stand. His strength gradually returned, and in 
fifty minutes’ time he was all right. I 11 this experiment there 
was no stertorous breathing, nor frothing at the mouth. 
June 13th, at 7.38 a.m.—Forty minims of acid were given to 
a little dog; he immediately staggered and fell; got up and.fell 
again some three or four times. In three minutes he fell, and 
was unable to rise. In five minutes 5ij infusion of valerian was 
given. At 7.48 there was stertorous breathing, frothing at 
the mouth, pupils dilated and eyes bloodshot, and he lay 
quite helplessly. At 7.54 he attempted to rise hut could not; 
hut at 7.56 got up, but was unable to stand, and fell again. 
By 8 o’clock the symptoms began to wear off, and by 8.20 
he was quite himself again. 
