i?o 
PEOF. WALLEY. 
It may not be uninteresting here to first recall briefly tlu 
ormer method of Pasteur for rendering dogs refractory to the 
( isease, as presented in his communication to the French Acad- 
emy on May 20, 1884. This first method was, briefly, as follows: 
lhe rabic virus obtained from the spinal cord of a rabid dog was 
first attenuated by passing it through a series of monkeys, and 
t ien, as the virulence is increased again by its transmission 
through rabbits, it was graded up to the desired degree of viru¬ 
lence by the subsequent inoculation with it of one or more rab¬ 
bits. In rendering dogs refractory to rabies they were first 
inoculated with a virus obtained from the first of the rabbits 
inoculated from the last of the series of monkeys. At the same 
time with the inoculation of the dog a second rabbit is inoculated. 
le dog receives his second inoculation from the virus obtained 
from the second rabbit, and at the same time a third rabbit is 
inoculated with this same material. The third and last inocu- 
ation of the dog is made with the virus obtained from the third 
rabbit. “At this time,” Pasteur says, “the dog has been render¬ 
ed entirely refractory to rabies.” In this same communication, 
in 1884, lie says: “I believe I can surely bring about a refractory 
state m the human being before the mortal disease appears in 
consequence of a bite.” 
(To be continued.) 
VENEREAL DISEASES IN THE LOWER ANIMALS. 
head by Piofessor Walley before the Scottish Metropolitan Veterinary Medical 
Mr. President and Gentlemen.— In bringing before jour 
notice the subject of “ Venereal Disease in the Lower Animals,” 
I may state at once that I have several objects in view. The first 
of these is to inquire as to what extent our domestic animals are 
liable to such infections. The second is as to whether we are 
justified, in the present state of our knowledge ., in assuming that 
they suffer from conditions allied to those which are characteristic 
of syphilis in man. The third is to direct attention to a method 
of treating intractable venereal sores in the dog which is both sure 
and effectual. 
