why pasteur’s vaccine fails to prevent hog cholera. 175 
ill 
mercury, and the usual local applications, and nitrate of silver 
and sulphate of copper, a lengthened trial, I determined upon try¬ 
ing the effects of castration. My reason for performing the 
operation was that 1 observed whenever I manipulated the animal 
chordee became very marked, and this was followed by extreme 
vascularity of the penis and particularly of the tissues involved in 
the ulcerative process. In my own mind I came to the conclu¬ 
sion that if priapism were prevented this periodical hypergemia 
would be done away with and rest insured to the cells of the dis¬ 
eased parts. 
The operation was performed, the effects of it surpassed my 
most sanguine expectations, and the dog was quickly discharged 
cured. 
(To be continued .) 
WHY PASTEUR’S VACCINE FAILS TO PREVENT HOG 
CHOLERA.* 
By D. E. Salmon. 
— 
In my former communication on this subject was given an ac¬ 
count of an experiment made by the Bureau of Animal Industry 
with Pasteur’s vaccine from which we concluded, some time in 
advance of the termination of the Nebraska experiment, that this 
vaccine could not be used to prevent hog cholera in the United 
States. In the first place, whether this vaccine is reliable when 
t leaves the laboratory of the great French chemist, or not, it 
certainly was not in a condition to give reliable results when it 
,’eached us, although it had probably not been prepared longer 
:han three weeks when it was used. The first vaccine was of 
ibout the strength which we expected it would have, but the 
second vaccine was weaker than the first, instead of being stronger, 
is it should have been. This fact we do not understand, and it 
seems to us that, as both were subjected to the same journey, we 
ire justified in entertaining the suspicion that they did not have 
he proper relative conditions of vigor when they left France. At 
ill events, the vaccination was a failure, and the vaccinated hogs 
i- 
Reprint from the Breeders' Gazette, May 20, 27, June 3, 10, 1886. 
