THE AETIOLOGY OF RABIES. 
217 
--—--- 
incubation period of seven days) which has been preserved in 
try air for about fourteen or fifteen days, and has thus been 
Drived of all its virulence. On the following day a cord twelve 
thirteen days old is used, and on the succeeding days the inoc- 
tions resolve themselves into about the following order: 
3d day, spinal cord 11 days old. 
9 “ “ 
7 u a 
6 u <( 
5 “ “ 
4 a a 
3 “ “ 
2 “ « 
1 day “ 
Ibis is about the order followed, more inoculations being here 
'Cribed than are perhaps essential or usually employed in prac- 
5. The inoculations with the cords which have lost their viru- 
4th 
a 
a 
a 
5th 
a 
a 
a 
6 th 
tt 
a 
a 
7th 
a 
4t 
a 
8 th 
it 
a 
a 
9 th 
a 
a 
a 
10 th 
a 
a 
ti 
11th 
a 
u 
it 
ee through the process of desiccation gradually render the 
mal insusceptible to the most virulent forms of the virus, so 
t, finally, no symptoms follow inoculations with virus which 
•duce rabies in dogs with great certainty in from eight to ten 
r s, when the animals have not been previously protected by 
dilation with the less virulent cords. In this manner dogs may 
rendered refractory to rabies, even when they are subsequently 
culated, underneath the dura mater after trephining, with the 
st virulent virus. 
The efficacy of this method was proved by subjecting fifty 
to these inoculations, with success in every case in rendering 
animals refractory to rabies. After having arrived at these 
ilts, Pasteur felt justified, after consultation with Dr. Vulpian 
• Dr - Grancher, in subjecting to the treatment a boy, Joseph 
istei by name, who had been bitten by a rabid dog and who 
xpectedly presented himself at the laboratory for treatment on 
: y 6th. 
j 
This boy had been bitten on July 4th in fourteen places by a 
which was supposed to be undoubtedly rabid. Many of the 
1 mc * s were very deep, and a portion of them only had been 
