506 
FRANK S: BILLINGS 
semi-fluid in the small, and became thicker and thicker towards 
the rectum. The large vessels were much injected. Mesenterial 
lymph glands swollen, moist, and of a diffuse pink redness. 
I endeavored to inoculate a number of herds from the 
substance of the brain and medulla oblongata, but as it had 
to be done in the field and as there was a strong wind blow¬ 
ing, I did not meet with results worthy of reporting at this 
time, although one form of bacterial life was found to pre¬ 
dominate in the cultures. 
Subcutaneous inoculations of dogs with large quantities of 
a bouillon culture of this organism did not produce rabies, hut 
did produce a very singular form of general paralysis, which 
I am not satisfied to call dumb-rabies, as there was no drop¬ 
ping of the lower jaw, or any such appearance of the pharynx 
and larynx as are seen in rabies. 
1 do not consider the above experiments to have any value, as 
they are too full of objections, but if rabies was present in these 
cattle, as I am led to conclude, from the history and clinical symp¬ 
toms, I cannot but think that if the micro-organism is successfully 
isolated, that large quantities of a bouillon culture introduced sub¬ 
cutaneously, should produce a furious form of rabies in one of 
three dogs, when the small quantity of virus introduced by a bite 
is known to do it under natural conditions. I consider that all 
intra-cranial or meningeal inoculations are open to serious objec¬ 
tions, and that to produce rabies in experimental dogs, so that 
the proof shall be beyond question, we must introduce the cul¬ 
tivated organism in exactly the same manner as is done under 
natural conditions, and that if we have discovered the organisms, 
large quantities thus introduced should more surely produce 
rabies than the small quantities under natural conditions. 
But this is not all; if the dogs, thus inoculated, really become 
rabid to all appearances, we cannot say that we have induced the 
genuine disease until healthy dogs have been exposed to such 
dogs and bitten by them, and then, that rabies has developed in 
some of them in course of time. The above microscopical de¬ 
scription exactly corresponds to that of the second animal killed 
by me on the 28th of August, with the exception of the peculiar 
