512 
PATHOLOGICAL PHYSIOLOGY. 
teur’s assertion, still the best means to prevent rabies — human 
or canine—is to reduce the number of dogs to the smallest num¬ 
ber possible by means of a rigid tax and strict execution of the 
law , and by compelling every dog to wear a muzzle at all sea¬ 
sons of the year. 
PATHOLOGICAL PHYSIOLOGY. 
ON THE RESISTANCE OF THE VIRUS OF GLANDERS TO THE 
DESTRUCTIVE ACTION OF ATMOSPHERIC AGENTS AND OF 
HEAT. 
By Messes. Cadeao and Malet. 
We have tried first to realize the natural conditions which, in 
practice, destroy glandered virus or preserve its conditions, and 
we have thus examined how long the virulency lasts : first, in 
matters more or less rapidly dried and in the lung exposed to 
the air at various times of the year; second, in matters placed in 
an atmosphere saturated with humidity at the temperature of the 
air surrounding ; third, in matters mixed with water. Then we 
have studied the resistance of the virus to heat. 
We have thus observed that: first, it loses its virulency in 
matters exposed to free air after complete desiccation ; second, 
that it is rapidly destroyed by warm weather, and, on the con¬ 
trary, slowly by cold and damp ; third, that the virus rapidly 
dried preserves its virulency longer than when dried slowly; 
fourth, that glandered matters placed in a medium saturated with 
humidity at the surrounding temperature preserve their activity 
for a long time ; fifth, that the discharge of glanders placed in 
watering places may preserve its activity for eighteen days; 
sixth, that the simple throwing of boiling water upon glandered 
discharge does not destroy its virulency, and that this is destroyed 
when the discharge is dipped for two minutes only in water in 
ebullition, though it is not necessary to expose it to such elevated 
temperature to destroy it.— Semaine Medicate. 
